Browsing Genetics (Scholarly Publications) by Subject "Evolution"

Now showing items 1-4 of 4

    • Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe 

      Bradley, Daniel; Frantz, Laurent A.F.; Haile, James; Lin, Audrey T.; Scheu, Amelie; Geörg, Christina; Benecke, Norbert; Alexander, Michelle; Linderholm, Anna; Mullin, Victoria E.; Daly, Kevin G.; Battista, Vincent M.; Price, Max; Gron, Kurt J.; Alexandri, Panoraia; Arbogast, Rose-Marie; Arbuckle, Benjamin; Balasescu, Adrian; Barnett, Ross; Bartosiewicz, László; Baryshnikov, Gennady; Bonsall, Clive; Borić, Dušan; Boroneant, Adina; Bulatović, Jelena; Çarkirlar, Canan; Carretero, José-Miguel; Chapman, John; Church, Mike; Crooijmans, Richard; De Cupere, Bea; Detry, Cleia; Dimitrijevic, Vesna; Dumitrascu, Valentin; du Plessis, Louis; Edwards, Ceiridwen (2019)
      Archaeological evidence indicates that pig domestication had begun by ∼10,500 y before the present (BP) in the Near East, and mitochondrial DNA (mtDNA) suggests that pigs arrived in Europe alongside farmers ∼8,500 y BP. A ...

    • New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation 

      Mc Lysaght, Aoife (2015)
      The origin of novel protein-coding genes de novo was once considered so improbable as to be impossible. In less than a decade, and especially in the last five years, this view has been overturned by extensive evidence from ...

    • Ohnologs are overrepresented in pathogenic copy number mutations. 

      Mc Lysaght, Aoife (2014)
      A number of rare copy number variants (CNVs), including both deletions and duplications, have been associated with developmental disorders, including schizophrenia, autism, intellectual disability, and epilepsy. Pathogenicity ...

    • Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes 

      Mc Lysaght, Aoife (2020)
      The origin of ‘orphan’ genes, species-specific sequences that lack detectable homologues, has remained mysterious since the dawn of the genomic era. There are two dominant explanations for orphan genes: complete sequence ...