Browsing Genetics (Scholarly Publications) by Subject "RNAi, polymorphism, COL1A1, gene therapy, stem cell, Osteogenesis Imperfecta"
Now showing items 1-2 of 2
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RNAi of COL1A1 in mesenchymal progenitor cells
(Nature Publishing Group, 2004)Given that mutant COL1A1 is known to cause Osteogenesis Imperfecta (OI), tools to modulate COL1A1 expression are likely to be of significant therapeutic value. In this context, we have evaluated RNA interference (RNAi) as ... -
RP1 Consortium. Identification of the RP1 and RP10 (IMPDH1) genes causing autosomal dominant RP
(Springer, 2003)Given that mutant COL1A1 is known to cause Osteogenesis Imperfecta (OI), tools to modulate COL1A1 expression are likely to be of significant therapeutic value. In this context, we have evaluated RNA interference (RNAi) as ...