dc.contributor.author | BRADLEY, DANIEL GERARD MARY | |
dc.date.accessioned | 2011-01-19T17:21:15Z | |
dc.date.available | 2011-01-19T17:21:15Z | |
dc.date.issued | 2011 | |
dc.date.submitted | 2011 | en |
dc.identifier.citation | Ceiridwen J. Edwards, Catarina Ginja, Juha Kantanen, Lucia Perez-Pardal, Anne Tresset, Frauke Stock, European Cattle Genetic Diversity Consortium Luis T. Gama, M. Cecilia T. Penedo, Daniel G. Bradley,Johannes A. Lenstra, Isaac J. Nijman, Dual Origins of Dairy Cattle Farming Evidence from a Comprehensive Survey of European Y-Chromosomal Variation, PLoS ONE, 6, 1, e15922, 2011 | en |
dc.identifier.other | Y | |
dc.description | PUBLISHED | en |
dc.description.abstract | Background:
Diversity patterns of livestock species are informative to the history of agriculture and indicate uniqueness of breeds as relevant for conservation. So far, most studies on cattle have focused on mitochondrial and autosomal DNA variation. Previous studies of Y-chromosomal variation, with limited breed panels, identified two Bos taurus (taurine) haplogroups (Y1 and Y2; both composed of several haplotypes) and one Bos indicus (indicine/zebu) haplogroup (Y3), as well as a strong phylogeographic structuring of paternal lineages.
Methodology and Principal Findings:
Haplogroup data were collected for 2087 animals from 138 breeds. For 111 breeds, these were resolved further by genotyping microsatellites INRA189 (10 alleles) and BM861 (2 alleles). European cattle carry exclusively taurine haplotypes, with the zebu Y-chromosomes having appreciable frequencies in Southwest Asian populations. Y1 is predominant in northern and north-western Europe, but is also observed in several Iberian breeds, as well as in Southwest Asia. A single Y1 haplotype is predominant in north-central Europe and a single Y2 haplotype in central Europe. In contrast, we found both Y1 and Y2 haplotypes in Britain, the Nordic region and Russia, with the highest Y-chromosomal diversity seen in the Iberian Peninsula.
Conclusions:
We propose that the homogeneous Y1 and Y2 regions reflect founder effects associated with the development and expansion of two groups of dairy cattle, the pied or red breeds from the North Sea and Baltic coasts and the spotted, yellow or brown breeds from Switzerland, respectively. The present Y1-Y2 contrast in central Europe coincides with historic, linguistic, religious and cultural boundaries. | en |
dc.description.sponsorship | CJE was supported by the Enterprise Ireland Basic Research Grants Programme (project numbers SC/1999/409 and SC/2002/510). CG was supported by a grant from Fundac?o Portuguesa para a Ciencia e a Tecnologia (Ref. SFRH/BD/13502/2003). JK was supported by the Academy of Finland and the Finnish Ministry of Agriculture and Forestry (SUNARE-program and `Russia in Flux? program). LP-P was supported by grant BES-2006-13545. Collection of several samples was supported by the Resgen project 98?118 (1999?2002) funded by the European Union. This work was also part-funded by The Wellcome Trust (grant no. 047485/Z/96/Z), and a Eurocores OMLL Programme Grant via CNRS, France. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | en |
dc.language.iso | en | en |
dc.publisher | PLoS | en |
dc.relation.ispartofseries | PLoS ONE; | |
dc.relation.ispartofseries | 6; | |
dc.relation.ispartofseries | 1, e15922; | |
dc.rights | Y | en |
dc.subject | Genetics | en |
dc.subject | European Y-Chromosomal Variation | en |
dc.title | Dual Origins of Dairy Cattle Farming Evidence from a Comprehensive Survey of European Y-Chromosomal Variation | en |
dc.type | Journal Article | en |
dc.type.supercollection | scholarly_publications | en |
dc.type.supercollection | refereed_publications | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/dbradley | |
dc.identifier.rssinternalid | 70506 | |
dc.identifier.rssuri | http://dx.doi.org/10.1371/journal.pbio.1000568 | en |
dc.contributor.sponsor | Enterprise Ireland | en |
dc.identifier.uri | http://hdl.handle.net/2262/49580 | |