Medical Gerontology: Recent submissions
Now showing items 161-180 of 529
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The Lived Experience of Frailty: Beyond Classification and Towards a Holistic Understanding of Health
(2024)Purpose: Frailty is characterised by decreased physiological reserves and vulnerability to stressors. Although scales such as the Fried’s Frailty Phenotype (FP), Frailty Index (FI), and Clinical Frailty Scale (CFS) are ... -
Haemodynamic Parameters Underlying the Relationship Between Sarcopenia and Blood Pressure Recovery on Standing
(2023)Background: Sarcopenia, delayed blood pressure (BP) recovery following standing, and orthostatic hypotension (OH) pose significant clinical challenges associated with ageing. While prior studies have established a link ... -
Metabolic syndrome accelerates epigenetic ageing in older adults: Findings from The Irish Longitudinal Study on Ageing (TILDA).
(2023)Metabolic syndrome (MetS) is a risk factor for the development of diabetes, cardiovascular disease, and all-cause mortality. It has an estimated prevalence of 40 % among older adults. Epigenetic clocks, which measure ... -
Functional clustering of continuous cardiovascular and brain oxygenation signals during an active stand test in The Irish Longitudinal Study on Ageing (TILDA)
(2023)In this study, we performed K-shape functional clustering of two non-invasive continuous cardiovascular (systolic Blood Pressure: sBP) and brain oxygenation (left frontal lobe Tissue Saturation Index: TSI) times series ... -
Effect of immunology biomarkers associated with hip fracture and fracture risk in older adults
(2023)Osteoporosis is a skeletal disease that can increase the risk of fractures, leading to adverse health and socioeconomic consequences. However, current clinical methods have limitations in accurately estimating fracture ... -
Evaluation of the Timed Up and Go test for screening vulnerability and frailty in older cancer patients
(2023)Introduction. The need for comprehensive geriatric assessment (CGA) in older adults with cancer is increasing, which makes it necessary to have a screening instrument to identify those who would benefit from this ... -
Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline
(2023)Background: Physical activity and exercise have been suggested as effective interventions for the prevention and management of mild cognitive impairment (MCI) and dementia, but there are no international guidelines. Objectives: ... -
An evaluation ofthe Allostatic Load framework for quantifying differences inhealth and longevity
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, 2023)The Allostatic Load (AL) framework posits that chronic or repeated exposure to stressors can cause dysregulation of multiple interrelated physiological systems, which if prolonged, may ultimately lead to deteriorations in ... -
Evaluation of a 3-Item Health Index in Predicting Mortality Risk: A 12-Year Follow-Up Study
(2023)This study was carried out using a large cohort (N = 4265; 416 deceased) of older, community-dwelling adults from The Irish Longitudinal Study on Ageing (TILDA). The study compared the performance of a new 3-item health ... -
The Use of the World Guidelines for Falls Prevention and Management's Risk Stratification Algorithm in Predicting Falls in The Irish Longitudinal Study on Ageing (TILDA)
(2023)Background: the aim of this study was to retrospectively operationalise the World Guidelines for Falls Prevention and Management (WGFPM) falls risk stratification algorithm using data from The Irish Longitudinal Study on ... -
Interrupting Bedtime to Reverse Frailty Levels in Acute Care: A Study Protocol for the Breaking Bad Rest Randomized Controlled Trial
(2023)Background Hospitalized older patients spend most of the waking hours in bed, even if they can walk independently. Excessive bedrest contributes to the development of frailty and worse hospital outcomes. We describe the ... -
Comprehensive geriatric assessment and clinical outcomes of frail older adults with diffuse large B-cell lymphoma: a metanalysis
(2023)Introduction. Comprehensive geriatric assessment (CGA) is used to personalize cancer treatments in frail older adults. However, its utility to guide treatments in frail older patients with diffuse large B-cell lymphoma ... -
Identification of predictors of gait speeds in The Irish Longitudinal Study on Ageing using automated feature selection and explainable machine learning
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, 2023)This work reports the novel application of automated feature selection and explainable machine learning to identify and compare, in participants aged 50 years or over from wave 3 of The Irish Longitudinal Study on Ageing ... -
The Age-Old Question of ANCA-Associated Vasculitis
(Trinity College Dublin. School of Medicine. Medical Gerontology, 2023)Anti-Neutrophil Cytoplasmic Autoantibody (ANCA)-Associated Vasculitis (AAV) is a group of systemic autoimmune disorders characterised by severe inflammation of the small blood vessels. Unusually for an autoimmune disease, ... -
“Dancing with Atoms”: A tribute to Sheila Tinney
(2023)The authors present a short dynamic visualization titled “Dancing with Atoms”, produced in honor of the late Irish mathematical physicist Sheila Tinney (1918--2010), the first Irish-born and -raised woman to receive a ... -
Older Hospitalised Patients' Reported Confidence in Managing Discharge Needs: a Retrospective Observational Study
(2023)Objectives: To evaluate the introduction of a patient-reported outcome measure (PROM) of self-confidence in managing discharge needs in an acutely hospitalised older adult population. Methods: A retrospective service evaluation ... -
Residential Long-Term Care and the Built Environment: Balancing Quality of Life and Infection Control
(2023)Objectives: This article explores expert insights into residential long-term care (RLTC), specifically regarding the built environment, its impact on infection control (IC) measures and on resident, staff, and family ... -
Turkish version of the SHARE-Frailty Instrument for primary care: reliability and validity in the nursing home setting
(2023)In Turkey, physical frailty instruments have not been studied in the nursing home setting. We determined the reliability and validity of a Turkish version of the SHARE-Frailty Instrument for primary care (SHARE-FI) in ... -
Biomarkers of delirium risk in older adults: a systematic review and meta-analysis
(2023)Delirium is a neuropsychiatric syndrome associated with increased morbidity and mortality in older patients. The aim of this study was to review predictive biomarkers of delirium in older patients to gain insights into ... -
Characterising the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults with Long Covid
(2023)Objective: Orthostatic intolerance (OI) is common in Long Covid. Physical counterpressure manoeuvres (PCM) may improve OI in other disorders. We characterised the blood pressure-rising effect of PCM using surface ...
