Medical Gerontology: Recent submissions
Now showing items 221-240 of 529
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Comparison of gait speed reserve, usual gait speed, and maximum gait speed of adults aged 50+ in Ireland using explainable machine learning
(2021)Gait speed is a measure of general fitness. Changing from usual (UGS) to maximum (MGS) gait speed requires coordinated action of many body systems. Gait speed reserve (GSR) is defined as MGS–UGS. From a shortlist of 88 ... -
Longitudinal trajectories of pulse wave velocity and cognition in the Irish longitudinal study of ageing (TILDA)
(2021)Introduction: Arterial stiffness is a marker of vascular ageing and carotid–femoral pulse wave velocity (cf-PWV) is a standard measurement method. A raised cf-PWV in individuals has been associated cross-sectionally with ... -
Frail by Different Measures: A Comparison of 8-year Mortality in The Irish Longitudinal Study on Ageing (TILDA)
(2021)Purpose: We compared the ability of four frailty identification tools (frailty phenotype: FP; FRAIL scale; 32-item Frailty Index: FI; and Clinical Frailty Scale: CFS) to predict 8-year mortality in TILDA. Methods: We ... -
The Relationship between Radiological Paraspinal Lumbar Measures and Clinical Measures of Sarcopenia in Older Patients with Chronic Lower Back Pain
(2021)Objectives: Sarcopenia is postulated to be an influential factor in chronic low back pain. The aim of this study is to evaluate the relationship between traditional clinical measures of sarcopenia and novel radiographic ... -
Associations between Cardiovascular Signal Entropy and Cognitive Performance over Eight Years
(2021)In this study, the relationship between non-invasively measured cardiovascular signal entropy and global cognitive performance was explored in a sample of community-dwelling older adults from The Irish Longitudinal Study ... -
In their own words: The voices of Older Irish people in the COVID-19 pandemic
(The Irish Longitudinal Study on Ageing, Trinity College Dublin, 2021)Since COVID-19 was declared an international pandemic by the World Health Organisation (WHO) in March 2020 (HSE, 2021), older people have carried the greatest burden of serious infection and death from the virus. ... -
SART and individual trial mistake thresholds: predictive model for mobility decline
(2021)The Sustained Attention to Response Task (SART) has been used to measure neurocognitive functions in older adults. However, simplified average features of this complex dataset may result in loss of primary information and ... -
The Importance of Age in the Prediction of Mortality by a Frailty Index: A Machine Learning Approach in the Irish Longitudinal Study on Ageing
(2021)The quantification of biological age in humans is an important scientific endeavor in the face of ageing populations. The frailty index (FI) methodology is based on the accumulation of health deficits and captures variations ... -
ACE gene I/D polymorphism and severity of SARS-CoV-2 infection in hospitalized patients: a metanalysis
(2021)Background Hypertension and type 2 diabetes increase the risk of severe SARS-CoV-2 infection. On the other hand, homozygous ACE deletion polymorphism (DD) has been associated with these two diseases and risk of acute ... -
Relationship between serum 25-hydroxyvitamin D concentration and acute inflammatory markers in hospitalized patients with SARS-CoV-2 infection: a systematic review
(2021)INTRODUCTION: There is experimental and clinical evidence that the serum concentration of 25-hydroxyvitamin D [25(OH)D)] may decrease in acute systemic inflammatory responses; in this context, low values may not necessarily ... -
Involving older people in co-designing a primary-care intervention to reverse frailty and build resilience
(2021)Background: An essential consideration in health research is to conduct research with members of the public rather than for them. Public and patient involvement (PPI) of older people in research can improve enrolment, ... -
Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults
(2021)In this Specialty Grand Challenge, we outline our vision of the current challenges in the field of Network Physiology as applied to aging and frailty. An expected development in this field for the 21st century is the ... -
Sleep habits in older adults in Ireland: Associations with physical and cognitive function
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2021)Sleep acts as the rest cycle for the body, during which restorative processes such as muscle growth, repair and memory consolidation occur. Sleep duration and chronotype have been identified as areas of interest to improve ... -
Nursing homes during the COVID-19 pandemic: a scoping review of challenges and responses
(2021)Introduction: COVID-19 has caused unprecedented challenges in nursing homes. In this scoping review, we aimed to describe factors that contributed to the spread and mortality of COVID-19 in nursing homes and provide an ... -
A mixed-methods feasibility study of a sit-to-stand based exercise programme to maintain knee-extension muscle strength for older patients during hospitalisation
(2021)Objectives: To determine the acceptability of an exercise programme and to identify barriers and facilitators to compliance with the programme from the participants’ perspective. Methods: Patients ...
