| dc.contributor.author | Mc Lysaght, Aoife | en |
| dc.date.accessioned | 2011-11-16T11:49:03Z | |
| dc.date.available | 2011-11-16T11:49:03Z | |
| dc.date.issued | 2011 | en |
| dc.date.submitted | 2011 | en |
| dc.identifier.citation | Daniele Guerzoni, Aoife McLysaght, De Novo Origins of Human Genes, PLoS Genetics, 7, 11, e1002381, 2011 | en |
| dc.identifier.other | Y | en |
| dc.description | PUBLISHED | en |
| dc.description.abstract | Where do new genes come from? For a long time the answer to that question has simply been ?from other genes?. The most prolific source of new loci in eukaryotic genomes is gene duplication in all its guises: exon shuffling, tandem duplication, retrocopying, segmental duplication, and genome duplication. However, in recent years there has been a growing appreciation of the oft-dismissed possibility of evolution of new genes from scratch (i.e., de novo) as a rare but consistent feature of eukaryotic genomes | en |
| dc.language.iso | en | en |
| dc.relation.ispartofseries | PLoS Genetics | en |
| dc.relation.ispartofseries | 7 | en |
| dc.relation.ispartofseries | 11, e1002381 | en |
| dc.rights | Y | en |
| dc.subject | Genetics | en |
| dc.subject | Gene duplication | en |
| dc.title | De Novo Origins of Human Genes | en |
| dc.type | Journal Article | en |
| dc.type.supercollection | scholarly_publications | en |
| dc.type.supercollection | refereed_publications | en |
| dc.identifier.peoplefinderurl | http://people.tcd.ie/mclysaga | en |
| dc.identifier.rssinternalid | 75855 | en |
| dc.subject.TCDTheme | Genes & Society | en |
| dc.identifier.rssuri | http://dx.doi.org/10.1371/journal.pgen.1002381 | en |
| dc.identifier.orcid_id | 0000-0003-2552-6220 | en |
| dc.identifier.uri | http://hdl.handle.net/2262/60719 | |
