dc.contributor.author | KENNY, ROSE ANNE | en |
dc.contributor.author | LAWLOR, BRIAN | en |
dc.contributor.author | NI MHAOLAIN, AINE | en |
dc.contributor.author | ROMERO-ORTUNO, ROMAN | en |
dc.date.accessioned | 2013-08-26T11:07:58Z | |
dc.date.available | 2013-08-26T11:07:58Z | |
dc.date.issued | 2012 | en |
dc.date.submitted | 2012 | en |
dc.identifier.citation | Ni Mhaolain AM, Fan CW, Romero-Ortuno R, Cogan L, Cunningham C, Kenny RA, Lawlor B., Frailty, depression and anxiety in later life., International Psychogeriatrics, 24, 8, 2012, 1265 - 1274 | en |
dc.identifier.other | Y | en |
dc.description | PUBLISHED | en |
dc.description | PMID: 22333477 | en |
dc.description.abstract | Background: Anxiety and depression are common in older people but are often missed; to improve detection
we must focus on those elderly people at risk. Frailty is a geriatric syndrome inferring increased risk of poor
outcomes. Our objective was to explore the relationship between frailty and clinically significant anxiety and
depression in later life.
Methods: This study had a cross-sectional design and involved the assessment of 567 community-dwelling
people aged ?60 years recruited from the Technology Research for Independent Living (TRIL) Clinic,
Dublin. Frailty was measured using the Fried biological syndrome model; depressive symptoms were assessed
using the Center for Epidemiological Studies Depression Scale; and anxiety symptoms measured using the
Hospital Anxiety and Depression Scale.
Results: Higher depression and anxiety scores were identified in both pre-frail and frail groups compared to
robust elders (three-way factorial ANOVA, p ?0.0001). In a logistic regression model the odds ratio for
frailty showed a significantly higher likelihood of clinically meaningful depressive and anxiety symptoms even
controlling for age, gender and a history of depression or anxiety requiring pharmacotherapy (OR = 4.3; 95%
CI 1.5, 11.9; p = 0.005; OR = 4.36; 95% CI 1.4, 13.8; p = 0.013 respectively).
Conclusions: Our findings suggest that even at the earliest stage of pre-frailty, there is an association with
increased symptoms of emotional distress; once frailty develops there is a higher likelihood of clinically
significant depression and anxiety. Frailty may be relevant in identifying older people at risk of deteriorating
mental health. | en |
dc.description.sponsorship | The Technology Research for Independent Living
Centre focuses on the research of new technologies
to enable people to live independent lives for as long
as possible in the environment of their choosing.
The Centre is a joint initiative between Intel and
the Industrial Development Agency Ireland. The
Centre is an active research collaboration between
industry and academic partners including Intel,
Trinity College Dublin, University College Dublin
and the National University of Ireland Galway,
and represents a multidisciplinary team of up to
70 researchers including ethnographers, designers,
clinicians, economists and a range of scientists and
technologists. | en |
dc.format.extent | 1265 | en |
dc.format.extent | 1274 | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | International Psychogeriatrics | en |
dc.relation.ispartofseries | 24 | en |
dc.relation.ispartofseries | 8 | en |
dc.rights | Y | en |
dc.subject | frailty, anxiety, depression, elderly | en |
dc.subject.lcsh | frailty, anxiety, depression, elderly | en |
dc.title | Frailty, depression and anxiety in later life. | en |
dc.type | Journal Article | en |
dc.type.supercollection | scholarly_publications | en |
dc.type.supercollection | refereed_publications | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/rkenny | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/lawlorba | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/nimhaoai | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/romeroor | en |
dc.identifier.rssinternalid | 80140 | en |
dc.contributor.sponsor | ICGEE Programme | en |
dc.identifier.uri | http://hdl.handle.net/2262/67243 | |