Innate DNA Sensing Moves to the Nucleus

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Item Type:
Journal Article
Date:
2011
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OpenAccess
Citation:
Unterholzner, L. & Bowie, A.G., Innate DNA Sensing Moves to the Nucleus, Cell Host and Microbe, 9, 2011, 351 - 353
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Abstract:
It has been assumed that cells distinguish viral from cellular DNA due to the former's presence in the cytosol. However, in this issue, Kerur et al. (2011) propose that the DNA genome of Kaposi's sarcoma-associated herpesvirus (KSHV) is recognized inside the nucleus by the DNA sensor IFI16, leading inflammasome activation
URI:
http://hdl.handle.net/2262/68042
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Grant Number
Science Foundation Ireland (SFI)
Author's Homepage:
http://people.tcd.ie/agbowie
Description:
PUBLISHED
Author: BOWIE, ANDREW
Sponsor:
Science Foundation Ireland (SFI)
Type of material:
Journal Article
URI:
http://hdl.handle.net/2262/68042
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Series/Report no:
Cell Host and Microbe
9
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Full text available
Subject:
Kaposi's sarcoma-associated herpesvirus (KSHV)
Subject (TCD):
Immunology, Inflammation & Infection
DOI:
http://dx.doi.org/10.1016/j.chom.2011.05.001
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