Innate sensing of bacterial cyclic dinucleotides: More than just STING

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Item Type:
Journal Article
Date:
2012
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Citation:
Bowie, A.G., Innate sensing of bacterial cyclic dinucleotides: More than just STING, Nature Immunology, 13, 12, 2012, 1137-1139
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Abstract:
Bacterial cyclic dinucleotides are recognised by the innate immune system, leading to induction of type I interferons. The mammalian helicase DDX41 directly binds cyclic dinucleotides and mediates the signaling pathway to type I interferon induction.
URI:
http://hdl.handle.net/2262/68079
Author's Homepage:
http://people.tcd.ie/agbowie
Description:
PUBLISHED
PubMed ID: 23160208
Author: BOWIE, ANDREW
Type of material:
Journal Article
URI:
http://hdl.handle.net/2262/68079
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Series/Report no:
Nature Immunology
13
12
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Subject:
Innate immune system
Subject (TCD):
Cancer , Immunology, Inflammation & Infection
DOI:
http://dx.doi.org/10.1038/ni.2469
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