| dc.contributor.author | MARTIN, SEAMUS | en |
| dc.date.accessioned | 2015-02-16T16:20:18Z | |
| dc.date.available | 2015-02-16T16:20:18Z | |
| dc.date.issued | 2012 | en |
| dc.date.submitted | 2012 | en |
| dc.identifier.citation | Hollville, E., Martin, S.J., Greasing the path to BAX/BAK activation, Cell, 148, 5, 2012, 845-846 | en |
| dc.identifier.other | Y | en |
| dc.description | PUBLISHED | en |
| dc.description.abstract | BAX/BAK activation leading to mitochondrial outer-membrane permeabilization is a key commitment point in apoptosis. Chipuk et al. now identify two sphingolipids as specific cofactors for BAX/BAK activation that lower the threshold for apoptosis-associated cytochrome c release. Association of mitochondria with other cellular membrane compartments is required for BAK/BAX exposure to these sphingolipids. | en |
| dc.format.extent | 845-846 | en |
| dc.language.iso | en | en |
| dc.relation.ispartofseries | Cell | en |
| dc.relation.ispartofseries | 148 | en |
| dc.relation.ispartofseries | 5 | en |
| dc.rights | Y | en |
| dc.subject | BAX/BAK | en |
| dc.subject.lcsh | BAX/BAK | en |
| dc.title | Greasing the path to BAX/BAK activation | en |
| dc.type | Journal Article | en |
| dc.type.supercollection | scholarly_publications | en |
| dc.type.supercollection | refereed_publications | en |
| dc.identifier.peoplefinderurl | http://people.tcd.ie/martinsj | en |
| dc.identifier.rssinternalid | 83645 | en |
| dc.identifier.doi | http://dx.doi.org/10.1016/j.cell.2012.02.006 | en |
| dc.rights.ecaccessrights | openAccess | |
| dc.subject.TCDTheme | Immunology, Inflammation & Infection | en |
| dc.contributor.sponsor | Science Foundation Ireland (SFI) | en |
| dc.identifier.uri | http://hdl.handle.net/2262/73235 | |
