Neuro-inflammation is a key contributor to the pathogenesis of Parkinson’s disease (PD). Brain-resident microglia are dynamic cellular effectors of inflammation-mediated neurodegeneration in the Parkinsonian brain. Here ...

Breast cancer is the most common female cancer diagnosed worldwide. In 2018 alone, there were over 2 million new breast cancer cases diagnosed. In Ireland, breast cancer is the most commonly diagnosed cancer in women. In ...

Education is an essential part of care for patients taking oral anticoagulants. However, it may be time-consuming for health care providers and overwhelming for patients, and hence sometimes suboptimal. Technology-based ...

An understanding of the effect of processing on the solid-state properties of active pharmaceutical ingredients (APIs) is essential for product manufacturing success. During product development it is possible to induce ...

This research was prompted by concerns of Tallaght Hospital, a major teaching hospital in Dublin, Ireland, that the dosage regimen for teicoplanin in patients with haematological malignancy was suboptimal. Three studies ...

The aetiology of inflammatory bowel disease (IBD) is incompletely understood but it is generally accepted to involve a dysregulated intestinal immune response to commensal microbiota and an increase in intestinal permeability. ...

Glyceryl trinitrate is a nitrate, a potent coronary vasodilator which exerts its principal benefit by reducing venous return, which reduces left ventricular work. Vasodilation is also associated with the undesired effects ...

Quality Medication Use and the Population with Intellectual Disabilities and Behaviour Disorders. A Modified Delphi Technique to develop Quality Indicators and a Grounded Theory approach to information provided by people ...