Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 1101-1120 of 7000
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Activation of MnIIMnIII-Peroxides with Relevance to the Catalytic Cycle of Ib RNRs
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)The understanding of the catalytic cycle of Ib ribonucleotide reductases (RNRs) has been hindered by the inability to trap the species formed following reaction of superoxide (O2-) and the MnII2 active site. This unknown ... -
Corpus of Works submitted for Doctor of Science (Sc.D.)
(Trinity College Dublin. School of Medicine. Discipline of Histopathology, 2023) -
Applying geogenic methods and decision-making tools to model radon at local and regional scales.
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2023)Radon is an environmental health hazard for indoor environments, caves and underground mines exposure to which is related to an increased probability of developing lung cancer. Globally, radon is the second leading cause ... -
Exploring the use of Communities of Practice and Communities of Inquiry in online postgraduate Higher Education settings.
(Trinity College Dublin. School of Education. Discipline of Education, 2023)A supportive, collegial environment which fosters engagement and persistence is considered to be fundamental to learner success. Higher education online learning options are available to students which allows them to ... -
Piezoresistive Properties of 2D based Nanocomposites for Strain Sensing Applications
(Trinity College Dublin. School of Physics. Discipline of Physics, 2023)The superlative piezoresistive properties of nanomaterials and their composites have attracted great interest in the area of strain sensing. The field has grown exponentially over the past decade, benefiting from the ... -
An Investigation into the Accretion Processes of Young Stellar Objects
(Trinity College Dublin. School of Physics. Discipline of Physics, 2023)The way in which young stars form is complex and fascinating, and is anything but a smooth, continuous process. Studying their dramatic, and sometimes violent, early years of accreting and ejecting material is vital in ... -
Heinrich Events and the British-Irish Ice Sheet: evidences of palaeoceanographic changes in the Rockall Trough
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2023)The Porcupine Bank is an offshore plateau connected to the Irish Shelf west of Ireland. Its western flank is affected by several water masses associated with the Atlantic Meridional Overturning Circulation (AMOC) and other ... -
Aspects of Dose Optimisation and Diagnostic Efficacy Relating to Dental Cone Beam Computed Tomography (CBCT)
The increasing acceptance of CBCT as a standard form of dental diagnostic imaging is based upon its ability to produce multiplanar cross-sectional (3D) images at a level of resolution that, while not as high as conventional ... -
Competition Law and the Regulation of Non Controlling Minority Interests: The Regulatory Gap
(Trinity College Dublin. School of Law. Discipline of Law, 2023)This thesis explores the regulation of minority interests (both cross and common) under Irish and EU competition law. It examines the economic theories of harm regarding cross and common minority shareholdings which, in ... -
Persistency and genomic tools in forage grasses
Perennial ryegrass (PRG; Lolium perenne) is the most widely cultivated forage grass species in Ireland. Despite its widespread use, there have been meagre gains in the improvement of agronomically important traits, including ... -
Understanding the Role of MicroRNA-31 in Regulating Cellular Sensitivity to Chemoradiotherapy in Pancreatic Ductal Adenocarcinoma
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Pancreatic adenocarcinoma (PDAC) is a lethal malignancy with a poor survival rate. One main challenge regarding PDAC is resistance to chemotherapy and radiotherapy. Therefore, there is an urgent requirement to characterise ... -
Essays in Macroeconomics: An Analysis of the South African Financial System
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Economics, 2023)This thesis consists of three empirical essays analyzing the financial systems in South Africa. Chapter 1 constructs a financial conditions index (FCI) for South Africa, over the period January 2000 to April 2017, that can ... -
Automated Creation of Intra-Video Social Comments
(Trinity College Dublin. School of Engineering. Discipline of Electronic & Elect. Engineering, 2023)Live video comments, or ?danmu?, are an emerging social feature on Asian online video platforms. These time-synchronous comments are overlaid on the video playback and uniquely enrich the viewing experience, engaging ... -
A biomechanical analysis of cyclist collisions in Ireland
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)As both a mode of transport and recreational activity, cycling has well-known health, environmental, and economic benefits. For these reasons, it has been encouraged in many countries, including the Republic of Ireland. ... -
Advancing Mental Health Research Using Data Science: Investigating Vulnerability to Depression with Language and Network Analysis
(Trinity College Dublin. School of Psychology. Discipline of Psychology, 2023)Depression affects over 5% of the global population, yet treatments for depression are only effective in 30-50% of people. Changing the status quo requires an improved understanding of how depression manifests in real life. ... -
Tuneable plasmonic metasurfacesfor on-chip beam steering applications using vanadium dioxide
(Trinity College Dublin. School of Physics. Discipline of Physics, 2023)For centuries, optical components were created using bulk components of various refractive indexes where light accumulates phase over a path much longer than its wavelength. With the advent of nanofabrication techniques, ... -
Regulating Crowdlending: A Critical Analysis of the European Union?s ECSPR
(Trinity College Dublin. School of Law. Discipline of Law, 2023)In 2020, the EU made its first foray into crowdlending regulation with the European Crowdfunding Service Providers for Business Regulation. This thesis explores whether the ECSPR has adequately responded to its regulatory ... -
Curriculum, Accreditation and Transition Pathways; pupils with Intellectual Disabilities in Special Schools (Ireland)
(Trinity College Dublin. School of Education. Discipline of Education, 2023)The focus of this study was to explore what curriculum is available for students with ID, at Senior Cycle, in special schools in Ireland? Secondly, what are the accreditation outcomes for students with intellectual ... -
Structural Diversity in Metal-Organic Frameworks and Metal-Organic Polyhedra with 1,3,5-Triethynyl-Benzene Based Linkers
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)The study of metal-organic frameworks and metal-organic polyhedra is a rapidly evolving area of research. The research presented in this thesis serves to further our understanding of these advanced materials with the primary ... -
Enantioseparation and structural optimisation of b-lactams and stilbene analogues for the treatment of triple negative breast and chemoresistant colorectal cancers
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Triple negative breast cancer (TNBC) is characterised by an extremely aggressive clinical phenotype and minimal expression of typical breast cancer receptors such as the estrogen, progesterone or HER2 receptors.1, 2 Patient ...
