Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 1201-1220 of 7000
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Automorphic Symmetries, String integrable structures and Deformations
(Trinity College Dublin. School of Mathematics. Discipline of Pure & Applied Mathematics, 2022)We address the novel structures arising in quantum and string integrable theories, as well as construct methods to obtain them and provide further analysis. Specifically, we implement the automorphic symmetries on ... -
Physical activity, physical health and clinical phenotype in adults with moderate and severe haemophilia
(Trinity College Dublin. School of Medicine. Discipline of Physiotherapy, 2022)Haemophilia is an inherited bleeding disorder caused by a deficiency in procoagulant Factor VIII (Haemophilia A) or Factor IX (Haemophilia B). Disease severity is stratified according to basal clotting factor levels, as ... -
On the Synthesis and Utilization of geminal-Dimethyl Hydroporphyrins and Tetraphenylethylenes in Photodynamic Therapy
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Chapter 1 introduces the main concepts of this thesis: photodynamic therapy (PDT), chlorins and photosensitizer arrays. In the case of PDT multiple topics are discussed, namely, the qualities of an ideal photosensitizer, ... -
Toward a Digital Genetic Edition of James Joyce's 'Finnegans Wake' Chapter II.2
(Trinity College Dublin. School of English. Discipline of English, 2022)This thesis is intended as a minor contribution to the broader discussion of digital textual editing. It uses a case study of James Joyce¿s creative process during the composition of Chapter II.2 of Finnegans Wake as a way ... -
Sustainable bogs: Challenges in transition
(Trinity College Dublin. School of Natural Sciences. Discipline of Geography, 2022)In January 2021, Bord na Móna chief executive Tom Donnellan announced that the company had ended its peat production business. The closure of the industrial bogs has led to calls for a just transition for those affected. ... -
BRAIN: Brain Injury in Neonates
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)Despite advances in neonatal care leading to a dramatic reduction in mortality rates in recent decades, there have been comparatively modest improvements in neurodevelopmental outcomes for infants born with neonatal ... -
C-reactive protein as a prognostic factor in cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2022)Prognostication, the prediction of future outcomes, is a key aspect of cancer care but remains imprecise. An elevated serum C-reactive protein (CRP) is associated with high symptom burden, poor quality of life and shorter ... -
Waste of Time - Examining the Politics and Temporal Practices of Smart Cities Through Urban Sanitation Systems
In the contemporary city, everything from traffic signals to street lighting to bus shelters are becoming part of the Internet of Things (IoT). With the capacity for sensing and monitoring and the all-important generation ... -
Kitchen politics: a cultural history of Irish domestic servants in England and the United States, c. 1870-1945
This thesis examines the representation of Irish domestic servants in Anglo-American culture over the late nineteenth and early twentieth century. The perceived difficulties of managing domestic help were a prominent feature ... -
Mental Disorders in Older Adults Admitted to General Hospitals: Review of Patient, Service Provision and Environmental Factors
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)The prevalence of mental illnesses in older general hospital inpatients has been studied widely however data from the Irish population is lacking. Psychiatry of Old Age Liaison (`POA Liaison¿) services provide assessment ... -
Spatio-Temporal Processes for Volumetric Video Content Creation
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2022)Volumetric Video is an emerging media platform which has recently undergone many new captivating developments. It could arguably be stated that recent uptake of volumetric video in consumer media would suggest that the ... -
Unravelling the Pivotal Role of Atropisomerism for Cellular Internalization
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Atropisomerism presents an intriguing, often neglected, source of varied biological activity in drug development. For a stable atropisomeric drug mixture, assessment of individual atropisomers may reveal an individual ... -
An in vitro study evaluating the efficacy of a novel mount with torque control designed to tighten Osstell SmartPegs
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2022)Objectives: The aim of this study was to evaluate the effects that different transducer tightening methods have on implant stability quotient (ISQ) values. A secondary aim was to determine the reliability of ISQ measurements ... -
Perceptions of Clinical Anxiety Disorders among Adolescents in Ireland: An Exploration of Anxiety Literacy, Stigma and Help-Giving Intentions
(Trinity College Dublin. School of Psychology. Discipline of Psychology, 2021) -
Developing a Next Generation Readout System for Microwave Kinetic Inductance Detectors
(Trinity College Dublin. School of Physics. Discipline of Physics, 2022)Microwave Kinetic Inductance Detectors (MKIDs) are photon detectors based on superconducting resonators, capable of detecting single photons with inherent energy resolution and μs time resolution, while also allowing ... -
Health Technology Assessment of CD19 CAR T-Cell Therapies in the Irish Healthcare Setting.
(Trinity College Dublin. School of Medicine. Discipline of Pharmacology & Therapeutics, 2022)The aim of this research was to undertake health technology assessments of CD19 CAR T-cell therapies, tisagenlecleucel and axicabtagene ciloleucel. A bespoke cost-utility model was developed to examine the cost effectiveness ... -
Developing an Understanding of `Compromised Consent¿: How reconsideration of consent as a legal concept may inform a feminist theoretical framework for the introduction of `Nordic Model¿ prostitution laws and did inform the motivations of lawmakers in Ireland
(Trinity College Dublin. School of Law. Discipline of Law, 2022)The focus of this thesis is upon the development of prostitution law in Ireland leading up to and including the introduction of the so-called `Nordic model¿ approach into Irish law through Part 4 of the Criminal Law (Sexual ... -
The Perceived Effect of Covid-19 on Undergraduate Education in Oral Surgery - A Qualitative Study
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2022)Introduction Covid-19 has had a profound impact on all of our lives since it was first described in Wuhan in December 2019. Oral Surgery is a specialty which involves teaching undergraduate dental students skills required ... -
A detailed comparison of Functional Threshold Power (FTP) versus Blood Lactate Thresholds, Ventilatory Threshold and Critical Power, proceeded by a trained model for FTP using GxT data
(Trinity College Dublin. School of Medicine. Discipline of Anatomy, 2022)The role of the power-based cycling test called the Functional Threshold Power test (FTP) is examined in the current research project. The computed cycling FTP (c-FTP) is reported to represent the uppermost power output ... -
Improving Saliency Metrics for Channel Pruning of Convolutional Neural Networks
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2022)Channel pruning is an effective technique to reduce the size of Convolutional Neural Networks (CNNs). A decisive part of any pruning algorithm is its saliency metric. We propose different techniques to improve saliency ...