Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 1221-1240 of 7000
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A National Study of Leadership in the Irish Primary Sector: STEM Education and Wellbeing during Crisis
Principals are leaders in school communities and their role is becoming increasingly more autonomous. Specifically, the role of the principal is evolving given the continuous implementation of new reforms and policies. ... -
An Exploration of Students’ Experiences in one DEIS second level school
Existing qualitative studies on DEIS and the lived experiences of students in DEIS schools are limited, particularly at second level. There has not been much analysis of the ways in which the affective elements of education, ... -
Investigation of retinal thickness using optical coherence tomography: a prospective phenotype study of patients with inherited ataxia
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Inherited cerebellar ataxias (CA) are clinically and genetically heterogeneous disorders. A diverse range of ophthalmic abnormalities have been reported in different subtypes of CA and, although visual symptoms are not ... -
Health Leadership and Management Development in Malawi: Towards a Theory for Health Systems Strengthening
(Trinity College Dublin. School of Psychology. Discipline of Psychology, 2022)Background: Strong leadership and management capacity of Human Resources for Health (HRH) is key to a health system s performance. However, there is a dearth of evidence-based literature on the application of health ... -
Investigating the Role of Altered Energy Metabolism in the Therapeutic Response of Rectal Cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2022)Colorectal cancer (CRC) is the 3rd most commonly diagnosed cancer world-wide, accounting for an estimated 10% of all cancers diagnosed annually globally. One in three CRCs occur in the rectum. The standard of care for ... -
A stakeholders perspective on the 'kickstart to recovery' football programme in a community mental health service
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2022)Introduction: One in four Irish people will experience mental health difficulties. Those with mental illness often don t receive best practice physical healthcare due to the division between service areas in Ireland and ... -
Modelling, development and characterisation of Microwave Kinetic Inductance Detectors for optical astronomy
(Trinity College Dublin. School of Physics. Discipline of Physics, 2022)In this thesis I report on the research I carried out on the topic of Microwave Kinetic Inductance Detectors (MKIDs) over the last four years. After an introduction chapter and a literature review on MKIDs, Chapter 3 ... -
Development of modified nucleosides for targeting the DNA repair enzyme SNM1A
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Certain cancers exhibit upregulation of DNA interstrand crosslink repair pathways, which contributes to resistance to crosslinking chemotherapy drugs and poor prognoses. Inhibition of enzymes implicated in interstrand ... -
Magnetic investigations of Mn-based and Mn-free potential half metals
(Trinity College Dublin. School of Physics. Discipline of Physics, 2022)This thesis is concerned with an unusual category of magnetically ordered material, the zero moments ferrimagnetic half metal, which has potential for applications in thin film memory and logic devices. The materials are ... -
Reconstructing name : Lady Gregory's tragic Irish heroine
(Trinity College (Dublin, Ireland). School of English, 1999)This thesis discusses the development of historian, folklorist and dramatist Lady Gregory's dramatic technique in regard to her Folk-History plays, Kincora I and II, Dervorgilla, and Grania. The focus of the thesis is on ... -
Grasping Moving Objects: Adaptive Motion Through Tactile Sensing
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)The aim of this project is to explore how adaptive grasping motions, informed by real-time tactile feedback, can improve grasp robustness when grasping moving objects. It was hypothesised that an adaptive grasping motion, ... -
Social Entrepreneurship in the Irish State-funded Third Sector
(Trinity College Dublin. School of Business. Discipline of Business & Administrative Studies, 2022)The study seeks to determine the extent and nature of social entrepreneurship in a population of Irish third sector organisations (TSOs) in receipt of state funding, and to explain why some TSOs may be more socially ... -
Informed consent for third molar extraction; a comparison of conventional verbal consent versus video-assisted consent
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2022)Background: The goal of the informed consent process is to provide patients with the necessary educational information, defend their autonomy, and allow active involvement in treatment planning and decision-making. The ... -
Adrenergic, Circadian, and Dietary Regulation of Interleukin-17A Expression by Adipose Gamma-Delta T Cells
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)Adipose tissue is home to a unique population of IL-17A expressing Gamma-Delta T cells (Gamma-Delta17 T cells), which are necessary for maintaining body temperature during cold environmental temperatures. However, the ... -
Short-term wind power forecasting: standardization, evaluation and optimization of prediction uncertainty
(Trinity College Dublin. School of Engineering. Disc of Civil Structural & Environmental Eng, 2022)This thesis reports on research aimed at enhancing our understanding on wind power forecasting by investigating and proposing standards to evaluate such forecasts, quantifying the main sources of forecast error, and ... -
The perceived relevance and benefit of Personal Development modules for social care learners, social care workers and practice educator supervisors
Personal Development (PD) is a mandatory module across the four years of the B.A (Hons) in Social Care work (SCW) at Limerick Institute of Technology (LIT). The aim of this study was to examine if PD is relevant and ... -
The Molecular Mechanisms of rhIGF1 in the Treatment of Rett Syndrome and Related Disorders: Studies in Patients, Mouse and Cellular Models
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)Recombinant human Insulin-like Growth Factor 1 (rhIGF1) is an approved treatment for growth failure and IGF1 deficiency. IGF1 has multiple functions in the body including growth, cell survival, metabolism, ageing and ... -
Pre-clinical development of NOX2/ROS blood-based biomarker of TBI
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)There is an urgent need to develop predictive biomarkers for traumatic brain injury (TBI) to aid clinical diagnosis and treatment of head injury patients. NADPH oxidase 2 (NOX2) activity and oxidized biomarkers are being ... -
Prospective Study of a Novel Diagnostic Algorithm for Investigating and Managing Gastrointestinal Disease Through The Appropriate Use of Biomarkers and Wireless Based Capsule Endoscopy
This chapter gives a general outline of the thesis for better understanding of issues surrounding research areas and studies that have been performed. Lower Gastrointestinal (GI) Symptoms are common and often warrant further ... -
A Precision Medicine Approach to Natriuretic Peptide-Guided Risk Prediction and Treatment: A Retrospective Analysis in the STOP-HF Cohort
Introduction: Individual studies show that NP-guided treatment is an effective intervention for the prevention of HF. We hypothesised that this approach may be optimised utilising a precision medicine approach. Methods: ...
