Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 361-380 of 7000
-
Algorithms for subitemset isomorphisms and applications to sorting networks
(Trinity College (Dublin, Ireland). School of Computer Science & Statistics, 2016)Our work, presented in this thesis, is based on our curiosity for proving optimality of sorting networks. The only feasible method (so far) of proving optimality of sorting networks is to derive a so-called 'computer-assisted' ... -
Precise modification of 2D materials by gas ion beams
(Trinity College (Dublin, Ireland). School of Physics, 2017)Precise modification of the geometry, stoichiometry and crystal structure of two dimensional (2D) materials will be instrumental in future nanodevice fabrication. Here, ion beams focused to a sub-nanometre scale have been ... -
Cancer stem cells : the root of cisplatin resistance in non-small cell lung cancer
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2016)Lung cancer is the leading cause of cancer-related death in Ireland and worldwide. Despite advances in anti-cancer therapies, the overall 5-year survival for non-small cell lung cancer (NSCLC) remains poor (<15%). As such, ... -
The jurisdiction to tax Highly Virtual Enterprises
(Trinity College (Dublin, Ireland). School of Law, 2016)Research for this thesis commenced in September 2011, with earlier preliminary research taking place from October 2010. The onus for undertaking this research was a belief that the challenges to international tax law posed ... -
Development of a novel stem cell approach for corneal tissue engineering
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2016)Corneal transplantation is frequently used to restore vision following corneal damage or disease but is limited by the availability of suitable donor corneas. Tissue engineering offers a novel answer to this problem through ... -
Two-dimensional nanomaterials : characterising properties and structures in real environments
(Trinity College (Dublin, Ireland). School of Physics, 2017)This thesis discusses studies of several two-dimensional nanomaterials with a view to understanding their behaviour when exposed to environments similar to those they would experience in the laboratory and in applications. ... -
Innovation of a micro-hydropower turbine to recover energy from water distribution networks : exploration of a design and identification of its economic and environmental value
(Trinity College (Dublin, Ireland). Department of Civil, Structural and Environmental Engineering, 2016)Energy consumption in water distribution networks (WDNs) is a widely publicised problem, one which results in the industry contributing high carbon emissions to the environment. Ways in which the carbon emissions of the ... -
Amino acid-dependant mTORC1 and cMyc signaling is essential for Natural Killer cell metabolic and functional responses
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2017)Natural killer [NK) cells are innate cytotoxic lymphocytes that are essential to the immune response against virally infected and transformed cells. NK cells directly kill target cells through the release cytotoxic granules. ... -
Essays on bank development, income inequality and human capital inequality
(Trinity College (Dublin, Ireland). Department of Economics, 2016)The core of the thesis consists of three empirical papers. The first one is about the link between bank development, corruption and economic growth. The second and the third both talk about inequality and how it relates ... -
Investigation of immuno-regulatory mechanisms during Staphylococcus aureus colonisation and infection
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2016)1.1 Staphylococcus aureus infections and treatment options Staphylococcus aureus: (S. aureus) is a Gram-positive coccal bacterium. It is a facultative anaerobe which can be distinguished from other such staphylococci due ... -
Optimization of vehicle front shape for pedestrian protection
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2017)The design of a vehicle front has a significant influence on pedestrian injury risk in the event of a vehicle collision. Although significant progress has been made in understanding which features of vehicle design are ... -
A mirror and an explosion : mapping the spaces of Roberto Bolaňo's 2666
(Trinity College (Dublin, Ireland). School of English, 2016)This thesis analyses space and place across Roberto Bolano's 2666. It conducts an analysis of the architecture and the topography of the novel, addressing the ways in which Bolano's deployment of spatial images and his ... -
Stable isotope analysis of Dublin Bay food web
(Trinity College (Dublin, Ireland). Department of Zoology, 2017)Coastal ecosystems are being increasingly impacted by human activities. Among the main threats, eutrophication is a major issue worldwide which can lead to major dysfunctions such as the excessive development of opportunistic ... -
Magnetic thin films for spin-transfer torque applications
(Trinity College (Dublin, Ireland). School of Physics, 2016)Current-induced magnetisation reversal of a nanomagnet by spin-transfer torque (STT) is of great technological importance owing to the scalability of the switching mechanism. An application of the STT phenomenon is the ... -
Identification of novel immunomodulators in the Vaccinia virus genome
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2016)A crucial early step for the initiation of an effective anti-viral response after sensing the presence of viruses is the activation of the transcription factors nuclear factor kappa-B (NFkB) and interferon regulatory factors ... -
Understanding firms' marketing and financial metric use : the impact of contemporary data - evidence from the tourism industry
(Trinity College (Dublin, Ireland). Trinity Business School, 2016)Over several consecutive years, the accountability of the marketing function has been amongst the top research priorities of the Marketing Science Institute (MSI) and a core driver of metrics-based research. The objective ... -
The cost-effectiveness of Hepatitis C treatments in Ireland : a multi-technology assessment
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2016)Introduction Chronic Hepatitis C (HCV) is an important public health concern with an estimated 20,000 to 50,000 people infected in Ireland. Horizon scanning at the National Centre for Pharmacoeconomics in 2011 identified ... -
Control of floral meristem activity in the model plant Arabidopsis thaliana
(Trinity College (Dublin, Ireland). Department of Genetics, 2017)Over the past 30 years, the flower development has been one of the main model to study the genetic control of organogenesis in higher plants. The work on Arahidopsis thaliana has led to the proposal of the ABC model of ... -
Bi-stable flow in tube arrays
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2016)An experimental study of bi-stable flow has been performed. Three tube array geometries were used; two normal triangular tube arrays with pitch-to-diameter ratios (P/d) of 1.32 and 1.58 and a parallel triangular tube array ... -
Energy and environment : solid state simulation of novel photovoltaic and catalytic materials
(Trinity College (Dublin, Ireland). School of Chemistry, 2016)The current global dependence on fossil fuels as the world’s primary energy supply presents many disadvantages, including the limited nature of these resources, the harmful effects their combustion has on human health and ...
