Mechanical, Manufacturing & Biomedical Eng: Recent submissions
Now showing items 161-180 of 952
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The role of the biophysical cues on the initiation, progression and maintenance of a chondrogenic phenotype in human stem cells
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Articular Cartilage Tissue Engineering (AC TE) is a promising strategy for the treatment of small cartilage defects, however complete mimicry of the native tissue remains a significant challenge. Mechanical cues like dynamic ... -
A review on conductive polymers and their hybrids for flexible and wearable thermoelectric applications
(2021)There is a growing demand for flexible and wearable next-generation electronic devices that must be capable of bending and stretching under mechanical deformation. In this regard, energy harvesting technologies have ... -
Towards Integration of Two-Dimensional Hexagonal Boron Nitride (2D h-BN) in Energy Conversion and Storage Devices
(2022)The prominence of two-dimensional hexagonal boron nitride (2D h-BN) nanomaterials in the energy industry has recently grown rapidly due to their broad applications in newly developed energy systems. This was necessitated ... -
Nanoengineering Approaches to Tune Thermal and Electrical Conductivity of a BiSbTe Thermoelectric Alloy
(2022)Nanoengineering of thermoelectric (TE) materials is an effective approach todecouple their electronic and thermal transport properties, hence enhancing their TE efficiency. Nanoengineering strategies can significantly ... -
Microstructure and tribological properties of Al2O3 reinforced FeCoNiCrMn high entropy alloy composite coatings by cold spray
(2022)High entropy alloys (HEAs) are novel materials that have been extensively studied in recent years. In this work, Al2O3 particles reinforced FeCoNiCrMn HEA composite coatings were fabricated by cold spray. The microstructure, ... -
Improvement of tensile strength of cold sprayed Fe deposits via in-process powder preheating
(2022)Cold sprayed Fe deposits were manufactured with non-preheated and preheated powders, respectively. The microstructure of the deposits was characterized by electron backscattered diffraction. The tensile property of the ... -
Influence of processing parameters on density, surface morphologies and hardness of as-built Ti-5Al-5Mo-5V-3Cr alloy manufactured by selective laser melting
(2022)Demand for new Ti alloys for AM is immense. Ti–5Al–5Mo–5V–3Cr (wt%), a β type Ti alloy is chosen for this study as it possesses excellent properties. Samples are manufactured using SLM technique. Relative density, surface ... -
A Method for Optimal Reconstruction of Velocity Response Using Experimental Displacement and Acceleration Signals
(2007)An algorithm is developed which takes advantage of the positive characteristics of integration and differentiation operations which can produce an optimal time-domain estimate of a velocity signal when a displacement and ... -
Time-resolved high-dynamic-range particle image velocimetry using local uncertainty estimation
(2015)The dynamic velocity range of particle image velocimetry is the ratio of the maximum to the minimum resolvable displacement. Although many techniques have been developed in recent years to extend the dynamic range, flows ... -
Fundamental insights into the biomechanics of atherosclerotic plaque tissue: Determining possible new diagnostic measures of plaque vulnerability
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Carotid atherosclerotic plaque rupture is known to be a major contributor to ischaemic stroke cases. The development of atherosclerotic plaques within the vessel wall alters both the geometry and mechanical environment of ... -
A Biomechanical and Microstructural Analysis of Bovine and Porcine Pericardium for Use in Bioprosthetic Heart Valves
(2021)Background: Animal-derived pericardium is a key material that enables the successful clinical use of bioprosthetic heart valves. Recently, transcatheter heart valves have placed more emphasis on the enhancement of this ... -
Integrating melt electrowriting and inkjet bioprinting for engineering structurally organized articular cartilage
(2022)Successful cartilage engineering requires the generation of biological grafts mimicking the structure, composition and mechanical behaviour of the native tissue. Here melt electrowriting (MEW) was used to produce arrays ... -
Using AI for Loss Prediction in a Hybrid Meanline Modelling Method to Deliver Improved Turbocharger Map Prediction
(2021)Meanline modelling approaches remain attractive due to an unrivalled ability to predict full turbine performance maps quickly compared to high fidelity approaches such as CFD, especially in the preliminary design process. ... -
Methacrylated Cartilage ECM-Based Hydrogels as Injectables and Bioinks for Cartilage Tissue Engineering
(2022)Articular cartilage (AC) possesses a limited healing potential, meaning that untreated focal joint defects typically progress, leading to the development of degenerative diseases such as osteoarthritis. Several clinical ... -
Layer-specific stem cell differentiation in tri-layered tissue engineering biomaterials: Towards development of a single-stage cell-based approach for osteochondral defect repair
(2021)Successful repair of osteochondral defects is challenging, due in part to their complex gradient nature. Tissue engineering approaches have shown promise with the development of layered scaffolds that aim to promote cartilage ... -
Biofabrication of vasculature in microphysiological models of bone.
(2021)Bone contains a dense network of blood vessels that are essential to its homoeostasis, endocrine function, mineral metabolism and regenerative functions. In addition, bone vasculature is implicated in a number of prominent ... -
Affinity-bound growth factor within sulfated interpenetrating network bioinks for bioprinting cartilaginous tissues
(2021)3D bioprinting has emerged as a promising technology in the field of tissue engineering and regenerative medicine due to its ability to create anatomically complex tissue substitutes. However, it still remains challenging ... -
Biofabrication of Prevascularised Hypertrophic Cartilage Microtissues for Bone Tissue Engineering
(2021)Bone tissue engineering (TE) has the potential to transform the treatment of challenging musculoskeletal pathologies. To date, clinical translation of many traditional TE strategies has been impaired by poor vascularisation ... -
Measuring and Modeling Oxygen Transport and Consumption in 3D Hydrogels Containing Chondrocytes and Stem Cells of Different Tissue Origins.
(2021)Understanding how the local cellular environment influences cell metabolism, phenotype and matrix synthesis is crucial to engineering functional tissue grafts of a clinically relevant scale. The objective of this study was ... -
3D bioprinting of prevascularised implants for the repair of critically-sized bone defects
(2021)For 3D bioprinted tissues to be scaled-up to clinically relevant sizes, effective prevascularisation strategies are required to provide the necessary nutrients for normal metabolism and to remove associated waste by-products. ...
