Mechanical, Manufacturing & Biomedical Eng: Recent submissions
Now showing items 181-200 of 952
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Biofabrication and bioprinting using cellular aggregates, microtissues and organoids for the engineering of musculoskeletal tissues
(2021)The modest clinical impact of musculoskeletal tissue engineering (TE) can be attributed, at least in part, to a failure to recapitulate the structure, composition and functional properties of the target tissue. This has ... -
Hydrostatic Pressure Regulates the Volume, Aggregation and Chondrogenic Differentiation of Bone Marrow Derived Stromal Cells
(2021)The limited ability of articular cartilage to has motivated the development of tissue engineering strategies that aim to harness the regenerative potential of mesenchymal stem/marrow stromal cells (MSCs). Understanding ... -
Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages
(2021)Tissue healing and regeneration is a complex, choreographed, spatiotemporal process involving a plethora of cell types, the activity of which is stringently regulated in order for effective tissue repair to ensue post ... -
Using Tactile Sensing to Improve Performance when Grasping Moving Objects
(2021)To operate in unstructured settings, robots require control strategies that effectively respond to temporal changes in their environment. In the domain of robotic manipulation, most state-of-the-art approaches assume the ... -
An IoT Approach for Monitoring UV Disinfection Robots
(2021)The use of ultraviolet germicidal irradiation (UVGI) technology as a means of disinfecting hospitals and other frontline settings has increased significantly in the wake of the COVID-19 pandemic. Although the science of ... -
Development and Functional Assessment of a Decellularised Injectable Biomaterial Combined with Nasal Chondrocytes for Intervertebral Disc Regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Lower Back Pain (LBP) is known to be a major health issue worldwide with a significant socioeconomic impact and it is widely accepted that LBP is associated with degeneration of the intervertebral disc (IVD). IVD degeneration ... -
Density Optimisation & In-Situ Microstructure Decomposition of As-Built Selective Laser Melted Ti-6Al-4V
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Additive manufacturing of titanium provides many advantages over traditional methodologies such as the ability to produce complex parts at no additional cost. One such AM method, selective laser melting (SLM) is a powder ... -
Directional Solidification Experiments with the Transparent Model Alloy Neopentyl Glycol-35wt.%(D)Camphor
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)This thesis describes the development of an experimental facility in combination with image processing and computer vision techniques for the visualisation and characterisation of dendritic growth structures in the transparent ... -
BIOFABRICATION STRATEGIES TO GUIDE THE SELF-ORGANISATION OF BIOMIMETIC CARTILAGE AND OSTEOCHONDRAL TISSUES
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)The modest clinical impact of musculoskeletal tissue engineering (TE) can be attributed, at least in part, to a failure to recapitulate the structure, composition and functional properties of the target tissue. This has ... -
Developing Microphysiological Systems of Bone Development, Physiology, and Repair
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Accurate models of human tissues and organ systems are foundational in our efforts to better understand human physiology. In the context of bone, a number of in vitro and in vivo models have been developed that facilitate ... -
Development of localised process parameter control for repeatability in metal additive manufacturing
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Due to the many advantages associated with metal additive manufacturing (AM) processes, research into these technologies has grown significantly over recent years. However, repeatability and reproducibility are critical ... -
Numerical assessment of the performance of a wastewater pump under off-design operating conditions
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Pumps are often key elements of industrial processes, and are commonly used to move water in municipal water schemes and in wastewater treatment of industrial effluents, representing a substantial energy cost. In the ... -
A Novel Linear Air Amplifier Technology to Replace Rotary Fans in Data Center Server Rack Cooling
(2020)This paper investigates the potential of a novel linear airflow amplifier designed to replace rotary fans for various industries where their performance is undesirable like electronics cooling applications in compact data ... -
Heat Transfer Characterization of a Single Source Ultra-Low Flow Rate Electrospray
(2013)The development and optimization of two phase electrospray cooling is currently restricted,in part due to the insufficient knowledge of how the various parameters that define an electrospray interact ... -
Analytical heat conduction model of annular composite fins
(2018)A two-dimensional analytical heat conduction model of an annular composite fin has been carried out.The composite fins composed of a porous polyethylene core, a square aluminum insert,and metallic zinc coating layers, ... -
Composite heat sink LED cooling
(2018)Metal coating of 3D printed polymers is an attractive proposition for thermal dissipation of light emitting diodes, due to its high efficiency and markedly lower material costs than conventional aluminum heat sinks. ... -
Plume Characterisation of a Single Source Electrospray for Micro Electronic Cooling
(2014)Development and optimization of two phase electrospray cooling is an undeveloped topic, in part due to unavailable knowledge of how the various electrical, geometrical, thermal and hydraulic parameters influence both ... -
Fabrication of Composite Heat Sinks Consisting of a Thin Metallic Skin and a Polymer Core Using Wire-Arc Spraying
(2019)Three composite heat sinks in the shape of a disk, a cylinder, and a cylinder with vertically projecting fins were made by applying a thin (0.4 – 0.7 mm) zinc layer onto ABS polymer cores using wire-arc spraying. The ... -
The effect of prior long-term recellularization with keratocytes of decellularized porcine corneas implanted in a rabbit anterior lamellar keratoplasty model.
(2021)Decellularized porcine corneal scaffolds are a potential alternative to human cornea for keratoplasty. Although clinical trials have reported promising results, there can be corneal haze or scar tissue. Here, we examined ... -
Primary cilium-mediated MSC mechanotransduction is dependent on Gpr161 regulation of hedgehog signalling.
(2021)The benefits of physical loading to skeletal mass are well known. The primary cilium has emerged as an important organelle in bone mechanobiology/mechanotransduction, particularly in mesenchymal stem/stromal cells, yet the ...
