Browsing Pharmacy and Pharmaceutical Sciences by Date of Publication
Now showing items 1-20 of 622
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A study of pharmacy practice. Non-prescribed medicines sales and counselling 3
(Swedish Pharmaceutical Press, 1991) -
A study of the release of the amphoteric drug amoxycillin from biodegradable polymers
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2000)Poly-alpha-hydroxy-aliphatic esters constitute a group of biodegradable polymers which have been actively investigated over the past three decades for the sustained release of drug compounds. A literature review revealed ... -
Intestinal degradation and absorption kinetics of salmon calcitonin
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2000)The aim of this work was to investigate the intestinal degradation and absorption of a hydrophilic peptide, salmon calcitonin (sCT), and to evaluate the use of bile salt simple and mixed micellar systems as potential ... -
Mechanistic aspects of the degradation and drug release properties of poly-alpha-hydroxyl aliphatic ester nano- and microparticle
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2000)Particulate systems based on the polymers of lactic and glycolic acids have been extensively investigated as drug delivery technologies, particularly as vehicles to achieve controlled release. The release kinetics from ... -
Assessment of permeability enhancers for salmon calcitonin (sCT) across intestinal cell culture models
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2000)A large number of proteins are now being used or tested as therapeutic agents, enzyme inhibitors or antibodies to combat human disease, therefore they are receiving increased recognition for both their high activity at low ... -
Characterisation of drug-fatty acid composites and their use in drug delivery systems
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2000)Fatty acids are considered to be useful as carrier materials in the formulation of drug delivery systems. Literature on fatty acid systems, in particular, stearic acid, was reviewed, though in general, research in this ... -
An investigation on the therapeutic properties of novel compounds in models of asthma, inflammation and delayed type hypersensitivity
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2000)There are many drugs on the market for the treatment of asthma, inflammation and delayed type hypersensitivity (DTH), however few are disease modifying. The potential therapeutic effect of three novel compounds, 3C8, 6C6 ... -
An investigation of the role of the polyamines in epilepsy and cerebral ischaemia
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2001)The polyamines, spermine and spermidine, are ubiquitous in nature but are found in especially high concentrations in brain tissue. The polyamines are required for cell growth and differentiation but in high doses are ... -
The development, validation and application of analytical methods for the analysis of drugs of abuse
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2001)There are five chapters presented in this thesis. The first chapter deals with development and validation of a HPLC method for the analysis of MDMA in illicitly produced Ecstasy tablets. In all 100 tablets were analysed ...
