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dc.contributor.advisorDavis, Tony
dc.contributor.authorKelleher, Mary Rose
dc.date.accessioned2019-07-25T13:30:44Z
dc.date.available2019-07-25T13:30:44Z
dc.date.issued2002
dc.identifier.citationMary Rose Kelleher, 'Towards a comprehensive system for the recognition of double helical DNA : Components for base pair recognition in the major groove', [thesis], Trinity College (Dublin, Ireland). School of Chemistry, 2002, pp 200
dc.identifier.otherTHESIS 6822
dc.description.abstractThis thesis describes the attempted synthesis of sequence selective double-stranded DNA-binding ligands. It had been intended to provide a comprehensive DNA recognition system via two different tricyclic heterocyclic motifs. The (5,5,5) pyrrolo [2', 3' : 4, 5] thieno [3, 2-d] thiazole system 1.52 was proposed to recognise A-T/T-A base pairs, and the functionalised (6,4,6)-tricyclic heterocyclic system 1.56 would recognise G-C/C-G base pairs.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Chemistry
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12432929
dc.subjectChemistry, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleTowards a comprehensive system for the recognition of double helical DNA : Components for base pair recognition in the major groove
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 200
dc.description.noteTARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie
dc.identifier.urihttp://hdl.handle.net/2262/88907


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