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dc.contributor.authorMartin, Seamus
dc.date.accessioned2019-10-09T13:24:12Z
dc.date.available2019-10-09T13:24:12Z
dc.date.created2019en
dc.date.issued2019
dc.date.submitted2019en
dc.identifier.citationBoeltz, S., Amini, P., Anders, H.-J., Andrade, F., Bilyy, R., Chatfield, S., Cichon, I., Clancy, D.M,, Desai, J., Dumych, T., Dwivedi, N., Gordon, R.A., Hahn, J., Hidalgo, A., Hoffmann, M.H., Kaplan, M.J., Knight J.S., Kolaczkowska, E., Kubes, P., Leppkes, M., Manfredi, A.A., Martin, S.J., Maueroder, C., Maugeri, N., Mitroulis, I., Munoz, L.E., Nakazawa, D., Neeli, I., Nizet, V., Pieterse, E., Radic, M.Z., Reinwald, C., Ritis, K., Rovere-Querini, P., Santocki, M., Schauer, C., Schett, G., Shlomchik, M.J., Simon, H.-U., Skendros, P., Stojkov, D., Vandenabeele, P., Berghe, T.V., van der Vlag, J., Vitkov, L., von Kockritz-Blickwede, M., Yousefi, S., Zarbock, A., Herrmann, M. To NET or not to NET: current opinions and state of the science regarding the formation of neutrophil extracellular traps, Cell Death and Differentiation, 2019, 26, 3, 395 - 408en
dc.identifier.otherY
dc.descriptionPUBLISHEDen
dc.description.abstractSince the discovery and definition of neutrophil extracellular traps (NETs) 14 years ago, numerous characteristics andphysiological functions of NETs have been uncovered. Nowadays, thefield continues to expand and novel mechanisms thatorchestrate formation of NETs, their previously unknown properties, and novel implications in disease continue to emerge.The abundance of available data has also led to some confusion in the NET research community due to contradictory resultsand divergent scientific concepts, such as pro- and anti-inflammatory roles in pathologic conditions, demarcation from otherforms of cell death, or the origin of the DNA that forms the NET scaffold. Here, we present prevailing concepts and state ofthe science in NET-related research and elaborate on open questions and areas of disputeen
dc.format.extent395en
dc.format.extent408en
dc.language.isoenen
dc.publisherSpringer Natureen
dc.relation.ispartofseriesCell Death and Differentiation;
dc.relation.ispartofseries26;
dc.relation.ispartofseries3;
dc.rightsYen
dc.subjectNeutrophilsen
dc.subjectHistonesen
dc.subjectExtracellular trapen
dc.subjectCell death and immune responseen
dc.subjectImmune cell deathen
dc.subjectInflammationen
dc.subjectProteolysisen
dc.titleTo NET or not to NET: current opinions and state of the science regarding the formation of neutrophil extracellular trapsen
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/martinsj
dc.identifier.rssinternalid204580
dc.identifier.doihttp://dx.doi.org/10.1038/s41418-018-0261-x
dc.rights.ecaccessrightsopenAccess
dc.identifier.urihttps://www.nature.com/articles/s41418-018-0261-x
dc.identifier.urihttp://hdl.handle.net/2262/89662


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