| dc.contributor.advisor | Martin, Seamus | |
| dc.contributor.author | Cullen, Sean P. | |
| dc.date.accessioned | 2019-11-05T15:23:41Z | |
| dc.date.available | 2019-11-05T15:23:41Z | |
| dc.date.issued | 2009 | |
| dc.identifier.citation | Sean P. Cullen, 'Exploring the role of granzymes in the induction of apoptosis', [thesis], Trinity College (Dublin, Ireland). Department of Genetics, 2009, pp 216 | |
| dc.identifier.other | THESIS 8738 | |
| dc.description.abstract | Cytotoxic Lymphocytes (CTL) and Natural Killer (NK) cells provide the body
with a powerful defence against viral infection, intracellular pathogens and
tumor development. After identifying an infected or damaged cell, CTL/NK
cells kill their targets by two main pathways involving either the ligation of death
receptors or the granule exocytosis pathway. In the granule pathway, CTL/NK
cells transfer a battery of death proteases called granzymes to the target cell
cytoplasm. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). Department of Genetics | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb13908283 | |
| dc.subject | Genetics, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin. | |
| dc.title | Exploring the role of granzymes in the induction of apoptosis | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 216 | |
| dc.description.note | TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
| dc.identifier.uri | http://hdl.handle.net/2262/90067 | |
