Studies on asymmetric organocatalytic processes: desymmetrisation, kinetic resolution and dynamic kinetic resolution

Abstract

The design and synthesis of small organic molecules which effectively mimic the hydrogen-bonding capabilities of enzymes has recently become a flourishing branch of the fascinating, emerging area of organocatalysis. Herein we detail our contribution to the field which allowed the identification and development of a set of asymmetry inducing transformations mediated by chiral bifunctional derivatives of natural cinchona alkaloids.