Browsing Surgery (Theses and Dissertations) by Subject "Chemoresistance"
Now showing items 1-2 of 2
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Investigating the role of miRNAs in the resistance of oesophago-gastric cancer to cytotoxic therapy
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2025)Oesophago-gastric cancers are two of the most commonly diagnosed cancers and the majority of oesophageal adenocarcinoma (OAC) and gastric adenocarcinoma (GAC) patients are diagnosed at a late stage. The standard of care ... -
Understanding the Role of MicroRNA-31 in Regulating Cellular Sensitivity to Chemoradiotherapy in Pancreatic Ductal Adenocarcinoma
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Pancreatic adenocarcinoma (PDAC) is a lethal malignancy with a poor survival rate. One main challenge regarding PDAC is resistance to chemotherapy and radiotherapy. Therefore, there is an urgent requirement to characterise ...
