Chemistry (Theses and Dissertations): Recent submissions
Now showing items 81-100 of 435
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Nanostructured carbon-based materials as sustainable electrocatalysts for energy conversion applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Electrochemistry has recently gained increased attention as a versatile strategy for achieving challenging transformations at the forefront of organic chemistry. Electrochemistry’s unique ability to generate highly ... -
Naphthalimides Exhibiting Aggregation-Induced Emission for Bioimaging Applications
In this project, a 1,8-naphthalimide (Nap, compound 8) is functionalised with two triphenylamino (TPA) moieties which, by virtue of having multiple freely rotating aromatic rings, are capable of exhibiting aggregation-induced ... -
Generation and Reactivity of Late Transition Metal Hydr(oxo) Complexes Supported by Tripodal Carboxamidate Ligand
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Metal oxo complexes (M=O) are important mediators of oxidative transformations in biological systems.1 Their high reactivity and transient nature have limited their study, with only a handful of well characterized oxo ... -
Pyrrole-based Photosensitisers for Photomedicine. Synthesis, Photophysical and Photobiological Evaluation of Chlorins and Dipyrrin Complexes
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Photodynamic therapy (PDT) is a light activated therapy which involves a drug-photosensitiser (PS), light, and molecular oxygen. First, the PS is administered via a systemic or topical route and then it accumulates in the ... -
Computational Modelling and Design of Cathode Materials for Sustainable Energy Applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Unravelling the activity and selectivity of novel heterogeneous catalysts requires a deep understanding of the effects unfolding at the catalytic surface. Particularly, this thesis emphasises the relevance of dopant ... -
Semi-synthetic Approaches to N-Glycosylation: A Story of Thiol-Ene Methodology, and Interferon-γ
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)The following thesis, entitled “Semi-synthetic Approaches to N-Glycosylation: A Story of Thiol-Ene Methodology, and Interferon-γ” is composed of six chapters. The first chapter provides an overview of the key concepts ... -
Antimicrobial formulation and functionalization of photosensitizers for antimicrobial photodynamic therapy (aPDT)
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)To provide a long-lasting solution to infections affecting the current world scenario, antimicrobial photodynamic therapy (aPDT) offers a non-invasive means to destroy pathogenic microbes via formation of reactive oxygen ... -
Examination of the organocatalysed reactions between azides and cyclic anhydrides
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Azide is encountered in organic synthesis as both a functional group and as and an ion, and provides a valuable means of incorporating nitrogen into target compounds. The intrinsic nucleophilicity of azides can be beneficial, ... -
Methods Development for the Synthesis of Biologically Relevant Porphyrins and Porphyrin Rigid Linker Arrays
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)This research focuses on two main aspects: The synthesis of new derivatives of naturally occurring porphyrins and the preparation of non-natural chromophore-rigid linker conjugates as potential bioisosteres and mimics of ... -
Guanidine based derivatives as potential anti-infective agents: Tackling protozoal diseases and Mycobacterium tuberculosis
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Infectious diseases caused by microorganisms of the genus Trypanosoma (Human African Trypanomiasis-HAT), Leishmania (Leishmaniasis), Plasmodium (Malaria) and Mycobacterium (Tuberculosis) cause some of the deadliest human ... -
High-valent late transition metal complexes for hydrocarbon oxidation
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)"Saturated hydrocarbons constitute the main feedstocks for energy production but their oxidation to valuable fine chemicals is still very challenging. Therefore the design and optimization of new catalysts for the ... -
In Search of Highly Emissive Fully Organic Compounds for Application in Molecular Electronics
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)The contents of this thesis can be summarised with two separate undertakings, with an overall goal to design, synthesise, and study novel organic materials. The first undertaking (Chapter Two) required detailed synthetic ... -
Development of a robust throughput process for the production of PMMA membranes via a TIPS air casting method
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Lateral flow membranes (membranes that allow movement of fluid across the membrane rather than through it) play a crucial role in the functionality of immunoassay devices determining performance speed and assay reliability. ... -
Block Copolymer Thin Films: Self-Assembly of Large Molecular Weight Systems and the Fabrication of Novel Metal/Metal Oxide Nanomaterials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)The self-assembly of block copolymers (BCPs) is considered an excellent candidate to further the development and progression of nanoscale technologies. While lithographic applications remain a primary topic of focus for ... -
Towards Improved Characterisation and Synthesis of Two-Dimensional Transition Metal Dichalcogenides
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Two-dimensional (2D) transition metal dichalcogenides (TMDs) are a fast growing and highly researched area in modern materials science. The numerous potential advances, made possible by their oft-quoted, varied, and ... -
The Optimisation of Silicas: Pre-treatment, Grafting & Potential Devices
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Silica materials especially mesoporous silicas are prime candidates as materials which could help solve many issues currently existing such as rising CO2 levels as capture devices and rising levels of cancer worldwide ... -
Synthesis and Characterisation of Transition Metal Dichalcogenides and their Heterostructures
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Since the first isolation of graphene in 2004 the interest in 2D materials has exponentially grown. Two-dimensional layered materials demonstrate profoundly different properties when isolated in their mono- or few layer ... -
Synthetic Approaches towards Photoactive Metal-Organic Frameworks
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Metal-organic frameworks (MOFs) are a class of hybrid inorganic-organic materials. They are composed of metal-containing units linked by organic linkers through strong bonds, forming high dimensional frameworks. ... -
The Phase- and Shape-Controlled Synthesis of Metal Sulfide Nano- and Micromaterials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Chapter 1. Contains a literature review focusing on inorganic nano- and micromaterials with an emphasis on metal sulfides. The topics discussed include: the unique size and shape controlled properties of these materials, ... -
Development of Cu-based multicomponent quantum nanostructures
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)The main goal of this project was to develop novel Cu-based multicomponent quantum nanostructures with distinct morphologies and optical properties and explore their potential applications as materials for luminescent solar ...
