Browsing Clinical Microbiology (Theses and Dissertations) by Subject "Clinical Microbiology, Ph.D."
Now showing items 1-7 of 7
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Anti-infective strategies in Pseudomonas aeruginosa biofilm formation
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2014)P. aeruginosa infection is one of the main causes of lung function decline in patients with cystic fibrosis (CF). P. aeruginosa is associated with biofilm formation which can increase the rate of resistance to antibiotic ... -
Antimicrobial resistance and virulence in Escherichia coli bloodstream isolates : a phenotypic, genetic and genomic perspective
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2010)Extraintestinal pathogenic Escherichia coli (ExPEC) are a major cause of sepsis, with a high associated mortality. They are widely reported to be the most frequent Gram-negative bacterial pathogen recovered from bacteraemia ... -
Antimicrobial resistance in clinical isolates of Pseudomonas aeruginosa
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2011)Pseudomonas aeruginosa is one of the most feared Gram-negative bacterial pathogens. It is not only among the most frequently isolated Gram-negative organisms in bloodstream and wound infections, pneumonia, intra-abdominal-sepis ... -
Investigation of reduced susceptibility to glycopeptides among meticillin-resistant Staphylococcus aureus recovered in Ireland (1998-2004)
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2009)Meticillin-resistant Staphylococcus aureus (MRSA) isolates (n=3,189) from 2990 patients were studied by agar screening and the E-test™ macromethod to investigate reduced susceptibility to glycopeptides among six collections ... -
Investigations of Aspergillus infection in Cystic Fibrosis
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2015)Aspergillus fumigatus is a ubiquitous saprophytic fungus that is a pathogen in principally immunocompromised hosts. It is the most common fungal pathogen in Cystic Fibrosis (CF), most often associated with Allergic ... -
The role of beta-lactamase in low-level cephalosporin-resistant serratia marcescens
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2002)In enterobacteria, high-level cephalosporin resistance is commonly mediated by constitutive over-production or derepression of chromosomal AmpC β-lactamase. This derepression is frequently associated with mutations in ... -
The role of the Salmonella PagN protein in adhesion and invasion
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2015)Salmonella, an important genus of Gram-negative enteric bacteria, is the causative agent of many different diseases including Typhoid Fever and Gastroenteritis. Salmonella utilises multiple methods of invading mammalian ...