Psychiatry (Scholarly Publications): Recent submissions
Now showing items 21-40 of 363
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Derivation of four iPSC lines from a male ASD patient carrying a deletion in the middle coding region of NRXN1α gene (NUIGi039-A and NUIGi039-B) and a male sibling control (NUIGi040-A and NUIGi040-B)
(2021)NRXN1 deletions are commonly found in autism spectrum disorder (ASD) and other neurodevelopmental/neuropsychiatric disorders. Derivation of induced pluripotent stem cells (iPSCs) from different diseases involving different ... -
PICLS Staff Manual
(Prison Inreach & Court Liaison Service, NFMHS Central Mental Hospital, 2017) -
Attention Deficit Hyperactivity Disorder (ADHD) and 5-HT2C receptor: A slight increase in the transmission of Cys23 to ADHD cases
(1999)Recent evidence suggests that interaction with and balancebetween serotonergicand dopaminergic neurotransmissionis important in the mediation of hyperactive behaviour.Animal model studies have ®rmly implicated the genes ... -
Executive Function in Routine Childhood ADHD Assessment
(2010)Aims: To determine the metacognitive deficits and behavioural and emotional regulation deficits among a group of children undergoing treatment for ADHD and to compare these with the hyperactivity/inattentive and behavioural ... -
Developmental comorbidity assessment in childhood ADHD
(2003)Introduction: Childhood ADHD typically presents with comorbidites. Assessment tools for developmental screening vary greatly in length and complexitity, and parental preference has an impact on the usefulness of clinical ... -
In God we trust? Organised religion and personal beliefs as resources and coping strategies, and their implications for health in parents with a child on the autistic spectrum
(1999)This paper is part of a larger study looking at the impact on 60 families of having a child with autistic spectrum disorder. Here the roles played by organised reliagion and personal belief and their relationship with ... -
Screening for autistic spectrum disorder at the 18-month developmental assessment: a population-based study
(2007)The objectives of this study were to assess the feasibility of administering the CHecklist for Autism in Toddlers (CHAT) at the 18-month developmental check, estimate the prevalence of screening positive for autism at the ... -
Autistic Tendencies: The Consequences for Our Culture
(2006)Professor Michael Fitzgeraldtalks withJoe Griffinabout the powerful impact, both positive and negative, of autistic thinking in diverse walks of life. -
The SNP ratio test: pathway analysis of genome-wide association datasets
(2009)Summary: We present a tool that assesses the enrichment of significant associations from genome-wide association studies (GWAS) in a pathway context. The SNP ratio test (SRT) compares the proportion of significant to ... -
Mental state decoding versus mental state reasoning as a mediator between cognitive and social function in psychosis
(2008)Theory of mind deficits in schizophrenia have been parsed into mental state reasoning and mental state decoding components. We report that mental state decoding as measured by the `Eyes task? better predicted social ... -
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
(2020)BACKGROUND: The prevalence of depression is higher in individuals with autoimmune diseases, but the mechanisms underlying the observed comorbidities are unknown. Shared genetic etiology is a plausible explanation for ... -
Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group
(2019)DNA methylation, which is modulated by both genetic factors and environmental exposures, may offer a unique opportunity to discover novel biomarkers of disease-related brain phenotypes, even when measured in other tissues ... -
No relationship between fornix and cingulum degradation and within-network decreases in functional connectivity in prodromal Alzheimer???s disease
(2019)Introduction: The earliest changes in the brain due to Alzheimer’s disease are associated with the neural networks related to memory function. We investigated changes in functional and structural connectivity among ... -
Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease
(2019)Introduction: The longitudinal trajectories of functional brain dynamics and the impact of genetic risk factors in individuals at risk for Alzheimer's disease are poorly understood. Methods: In a large-scale monocentric ... -
Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD
(2019)Introduction: Successful development of effective β-site amyloid precursor protein cleaving enzyme 1 (BACE1)–targeted therapies for early stages of Alzheimer's disease requires biomarker-guided intervention strategies ... -
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
(2018)Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding the genetic factors contributing to the shared and disorder-specific symptoms will be crucial for improving diagnosis and ... -
Epigenetic variance in dopamine D2 receptor: a marker of IQ malleability?
(2018)Genetic and environmental factors both contribute to cognitive test performance. A substantial increase in average intelligence test results in the second half of the previous century within one generation is unlikely to ... -
Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence.
(2019)Rates of cannabis use among adolescents are high, and are increasing concurrent with changes in the legal status of marijuana and societal attitudes regarding its use. Recreational cannabis use is understudied, especially ...
