Pharmacy and Pharmaceutical Sciences (Scholarly Publications): Recent submissions
Now showing items 361-380 of 452
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Nanostructured systems containing babassu (Orbignya speciosa) oil as a potential alternative therapy for benign prostatic hyperplasia.
(2013)The oil of babassu tree nuts (Orbignya speciosa) is a potential alternative for treatment and prophylaxis of benign prostatic hyperplasia. Improved results can be obtained by drug vectorization to the hyperplastic tissue. ... -
Twenty-first century mast cell stabilizers
(2013)Mast cell stabilizing drugs inhibit the release of allergic mediators from mast cells and are used clinically to prevent allergic reactions to common allergens. Despite the relative success of the most commonly prescribed ... -
Amorphous solid dispersions of sulfonamide/Soluplus® and sulfonamide/PVP prepared by ball milling
(2013)The aim of this paper is to investigate the physicochemical properties of binary amorphous dispersions of poorly soluble sulfonamide/polymeric excipient prepared by ball milling. The sulfonamides selected were sulfathiazole ... -
2-(Di-phenyl-methyl-idene)-2,3-di-hydro-1H-inden-1-one.
(2013)In the title mol-ecule, C22H16O, the indanone ring system is approximately planar with a dihedral angle between the fused rings of 5.13 (14)°. Two benzene rings are linked together at one side of a double bond, sitting on ... -
Interventions for improving medication reconciliation across transitions of care (Protocol)
(John Wiley & Sons, 2013-10-30)This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effect of medication reconciliation on medication discrepancies, patient related outcomes and healthcare utilisation ... -
miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer
(2014)BACKGROUND: While the treatment of HER2 over-expressing breast cancer with recent HER-targeted drugs has been highly effective for some patients, primary (also known as innate) or acquired resistance limits the success ... -
ISEV position paper: extracellular vesicle RNA analysis and bioinformatics.
(2013)Extracellular vesicles (EVs) are the collective term for the various vesicles that are released by cells into the extracellular space. Such vesicles include exosomes and microvesicles, which vary by their size and/or protein ... -
Isosteviol has beneficial effects on palmitate-induced cell dysfunction and gene expression.
(2012)BACKGROUND: Long-term exposure to high levels of fatty acids impairs insulin secretion and exaggerates glucagon secretion. The aim of this study was to explore if the antihyperglycemic agent, Isosteviol (ISV), is able ... -
Docetaxel-resistance in prostate cancer: evaluating associated phenotypic changes and potential for resistance transfer via exosomes.
(2012)Background Hormone-refractory prostate cancer remains hindered by inevitable progression of resistance to first-line treatment with docetaxel. Recent studies suggest that phenotypic changes associated with cancer may ... -
Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis.
(2013)Weighted gene coexpression network analysis (WGCNA) is a powerful 'guilt-by-association'-based method to extract coexpressed groups of genes from large heterogeneous messenger RNA expression data sets. We have utilized ... -
Platelets increase survival of adenocarcinoma cells challenged with anticancer drugs: mechanisms and implications for chemoresistance.
(2012)BACKGROUND AND PURPOSE: Cancer cells grow without the restraints of feedback control mechanisms, leading to increased cancer cell survival. The treatment of cancer is often complicated by the lack of response to ... -
Ethnopharmacology in Ireland: an overview
(2014)The aim of this review was to extract information of the book Medicinal Plants in Folk Tradition: An Ethnobotany of Britain & Ireland published in 2004 by Allen and Hatfield, to give an overview of plants with medicinal ... -
Analysis of platelet function: role of microfluidics and nanodevices
(2011)Platelet aggregation is essential for vascular haemostasis and thrombosis. To improve the therapy of arterial thrombotic disorders and identify novel therapeutic targets it is imperative to study basic mechanisms of platelet ... -
Potential for alcohol and drug interactions in older adults: evidence from the Irish longitudinal study on ageing
(2014)Background Older adults are susceptible to adverse effects from the concomitant use of prescription medications and alcohol. This study estimates the prevalence of exposure to alcohol interactive (AI) medications and ... -
Adhesion characteristics and stability assessment of lectin-modified liposomes for site-specific drug delivery
(2008)Carbohydrate moieties of the cellular glycocalyx have been suggested to play an important role in biological recognition processes during pathologic conditions, such as inflammation and cancer. Herein, we describe ... -
Medicines use review pilot project
(Primary Care Group, Health Service Executive (HSE), 2012) -
Baseline study of Community Pharmacy Practice in Ireland - report
(Pharmaceutical Society of Ireland, 2011) -
Hospital Pharmacy in Ireland
(Pharmaceutical Society of Ireland, 2012) -
Non-Prescription Medicinal Products containing codeine: guidance for pharmacists on safe supply to patients
(Pharmaceutical Society of Ireland, 2010)