RSS 1.0Radiation Therapy
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Radiation Therapy (Live Theses)
Radiation Therapy (Live Theses) -
Radiation Therapy (Scholarly Publications)
Radiation Therapy (Scholarly Publications) -
Radiation Therapy (Theses and Dissertations)
Radiation Therapy (Theses and Dissertations)
Recent Submissions
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Quantitative Image Analysis for the Assessment of Parotid Gland Damage and Toxicity Prediction Following Radiotherapy to the Head and Neck
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2024)Patients treated with radiotherapy for head and neck cancer experience debilitating xerostomia and sticky saliva, caused by damage to the parotid glands. Currently predicting this toxicity is limited by the inability of ... -
PO-1263: What every radiation oncologist should know about geriatric oncology: A global expert consensus
(2020)Purpose or Objective To establish a dedicated Radiation Oncology- Geriatric Oncology global curriculum for radiation and clinical oncology trainees worldwide Material and Methods An international Delphi Expert Consensus ... -
The Impact of Geriatric Assessment on Patient Outcomes in Radiation Oncology: A Pilot Study.
(2020)Introduction: The objective of this pilot study was to obtain preliminary data on the efficacy and feasibility of incorporating geriatric assessment (GA) into radiation oncology (RO) with regard to patient outcomes and ... -
Investigating the Needs and Concerns of Lesbian, Gay, Bisexual, Transgender, Queer, or Questioning Cancer Patients
(2024)The needs and concerns of lesbian, gay, bisexual, transgender, queer, or questioning (LGBTQ+) patients with cancer remain poorly understood. This is important as LGBTQ+ patients have an elevated risk of developing certain ... -
Exploring Hypoxia in Prostate Cancer With T2-weighted Magnetic Resonance Imaging Radiomics and Pimonidazole Scoring
(2023)Background/Aim: Radiomics involves high throughput extraction of mineable precise quantitative imaging features that serve as non-invasive prognostic or predictive biomarkers. High levels of hypoxia are associated with a ... -
In vitro and in vivo characterization of [64Cu][Cu(elesclomol)] as a novel theranostic agent for hypoxic solid tumors
(2023)Hypoxic tumors are associated with therapy resistance and poor cancer prognosis, but methods to detect and counter tumor hypoxia remain insufficient. Our purpose was to investigate 64Cu(II)-elesclomol ([64Cu][Cu(ES)]) as ... -
Creating a 3D-printed pelvic phantom to explore the impact of Magnetic Resonance (MR) scanner noise in radiomics analysis, a technical note.
(2024)Reproducibility of radiomics features necessitates that scanner noise be considered prior to feature extraction. Phantom research provides the opportunity for such ‘ground truth’ measurements, without the additional ... -
Time, location and function of hypoxia-inducible factors are critical to therapeutic tumour response
(2024)Multiple lines of evidence confirm isoforms the strong association between the presence of hypoxia in solid tumours and poorer outcomes ihn patients with cancer resulting from both more aggressive tumour cell behaviour and ... -
Prehabilitation for Patients with Cancer Undergoing Radiation Therapy: a Scoping Review
(2024)Aims: Prehabilitation is a process of identifying and assessing factors that could compromise the physical and psychological health of patients undergoing cancer treatment and implementing an intervention to combat such ... -
A joint physics and radiobiology DREAM team vision – Towards better response prediction models to advance radiotherapy
(2024)Radiotherapy developed empirically through experience balancing tumour control and normal tissue toxicities. Early simple mathematical models formalized this practical knowledge and enabled effective cancer treatment to ... -
In silico analysis of overall survival with YBX1 in male and female solid tumours
(2024)The Y-box binding protein-1 (YBX1) gene codes for a multifunctional oncoprotein that is increasingly being linked to the regulations of many aspects of cancer cell biology. Disparities in treatment outcomes between male ... -
Tumours have a sex: impact on the response of bladder cancer and lung adenocarcinoma to therapy
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2024)Background: The 23rd pair of chromosomes in humans is responsible for sex determination, in which humans are categorised as female (XX chromosomes) or male (XY chromosomes). While phenotypically, male and females are ... -
Radiotherapy: Seizing the opportunity in cancer care
(ESTRO, 2019)The incidence of cancer is increasing, resulting in a rising demand for high‑quality cancer care. In 2018, there were close to 4.23 million new cases of cancer in Europe, and this number is predicted to rise by almost ... -
Evaluation of an eLearning teaching innovation to assist clinical radiation therapy educators in the provision of student feedback
(2021)Background: Clinical placement is an integral part of the Radiation Therapy undergraduate programme. Feedback and formative assessment during clinical placement are regarded as key to developing clinical skills and ... -
Magnetic Resonance Imaging Radiomics - Towards the Personalisation of Radiation Therapy for Prostate Cancer.
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2020)The primary function of a predictive biomarker is to accurately determine the outcome of a specified treatment. Radiomics is a developing field that involves advanced image analysis and high throughput extraction of ... -
Multiplex profiling identifies clinically relevant signalling proteins in an isogenic prostate cancer model of radioresistance
(2019)The exact biological mechanism governing the radioresistant phenotype of prostate tumours at a high risk of recurrence despite the delivery of advanced radiotherapy protocols remains unclear. This study analysed the protein ... -
The development, implementation and evaluation of frailty assessment in oncology
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2020)Over the last number of decades, treatment outcomes from cancer care have improved dramatically. However, these improvements have mostly benefitted younger patients, or relatively robust older adults, rather than the entire ... -
The European Society of Radiotherapy and Oncology (ESTRO) European Higher Education Area levels 7 and 8 postgraduate benchmarking document for Radiation TherapisTs (RTTs)
(2018)This guideline details the European Higher Education Area Levels 7 and 8 Postgraduate benchmarking document for Radiation TherapisTs (RTTs). The purpose of this benchmarking document is to assist higher education institutes ... -
A review of the Best Practice in Radiation Oncology project from 2008 to 2018
(2018)The European Society of Radiotherapy and Oncology (ESTRO)/International Atomic Energy Agency (IAEA) Best Practice in Radiation Oncology-a project to train RTT trainers has reached its ten year anniversary and will commence ... -
Introduction to the ESTRO European Qualifications Framework (EQF) 7 and 8: Benchmarking Radiation Therapist (RTT) advanced education
(2018)Innovations in radiotherapy practice continue to develop and expand. With this comes a requirement for suitably educated Radiation TherapisTs (RTTs) to expand their scope of practice and work at advanced levels within ...
