Browsing Radiation Therapy by Title
Now showing items 1-20 of 32
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Clinical Oral Examinations: Assessment of Competency in Radiation Therapy
(2009)Matching assessment strategies to learning outcomes in radiation therapy education is of the utmost importance. Assessing clinical competence requires that `competence? be clearly defined prior to the start of any clinical ... -
Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer.
(2015)This review compares the safety and efficacy of boron neutron capture therapy (BNCT) in the treatment of previously irradiated, inoperable locoregional recurrent HNC patients and compares BNCT against the standard treatment ... -
Creating a 3D-printed pelvic phantom to explore the impact of Magnetic Resonance (MR) scanner noise in radiomics analysis, a technical note.
(2024)Reproducibility of radiomics features necessitates that scanner noise be considered prior to feature extraction. Phantom research provides the opportunity for such ‘ground truth’ measurements, without the additional ... -
Current and Future Trends in the Management of Gastrointestinal Cancers
(2013)The Study Day was aimed at frontline radiotherapy staff who interact with gastrointestinal patients on a daily basis. The aim was to inform participants of the current and future practice in diagnosis, management and ... -
The development, implementation and evaluation of frailty assessment in oncology
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2020)Over the last number of decades, treatment outcomes from cancer care have improved dramatically. However, these improvements have mostly benefitted younger patients, or relatively robust older adults, rather than the entire ... -
DNA mismatch repair and low dose hyper-radiosensitivity in prostate cancer cells
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Radiation Therapy, 2010)Low-dose hyper-radiosensitivity (HRS) describes the excessive sensitivity of cells to radiation doses less than 0.3Gy. Evidence suggests that HRS may influence tumour response and normal tissue reactions after intensity ... -
ESTRO ACROP guidelines for positioning, immobilisation and position verification of head and neck patients for radiation therapists
(European Association of Nuclear Medicine, 2017) -
The European Society of Radiotherapy and Oncology (ESTRO) European Higher Education Area levels 7 and 8 postgraduate benchmarking document for Radiation TherapisTs (RTTs)
(2018)This guideline details the European Higher Education Area Levels 7 and 8 Postgraduate benchmarking document for Radiation TherapisTs (RTTs). The purpose of this benchmarking document is to assist higher education institutes ... -
Evaluation of an eLearning teaching innovation to assist clinical radiation therapy educators in the provision of student feedback
(2021)Background: Clinical placement is an integral part of the Radiation Therapy undergraduate programme. Feedback and formative assessment during clinical placement are regarded as key to developing clinical skills and ... -
Exploring Hypoxia in Prostate Cancer With T2-weighted Magnetic Resonance Imaging Radiomics and Pimonidazole Scoring
(2023)Background/Aim: Radiomics involves high throughput extraction of mineable precise quantitative imaging features that serve as non-invasive prognostic or predictive biomarkers. High levels of hypoxia are associated with a ... -
Hypoxic Tumor Kinase Signaling Mediated by STAT5A in Development of Castration-Resistant Prostate Cancer.
(2013)In this study, we hypothesized that androgen-deprivation therapy (ADT) in prostate cancer, although initially efficient, induces changes in the tumor kinome, which subsequently promote development of castration-resistant ... -
The Impact of Geriatric Assessment on Patient Outcomes in Radiation Oncology: A Pilot Study.
(2020)Introduction: The objective of this pilot study was to obtain preliminary data on the efficacy and feasibility of incorporating geriatric assessment (GA) into radiation oncology (RO) with regard to patient outcomes and ... -
Improving non-invasive detection of prostate cancer using diffusion-weighted MRI
(European Association of Nuclear Medicine, 2016) -
In silico analysis of overall survival with YBX1 in male and female solid tumours
(2024)The Y-box binding protein-1 (YBX1) gene codes for a multifunctional oncoprotein that is increasingly being linked to the regulations of many aspects of cancer cell biology. Disparities in treatment outcomes between male ... -
In vitro and in vivo characterization of [64Cu][Cu(elesclomol)] as a novel theranostic agent for hypoxic solid tumors
(2023)Hypoxic tumors are associated with therapy resistance and poor cancer prognosis, but methods to detect and counter tumor hypoxia remain insufficient. Our purpose was to investigate 64Cu(II)-elesclomol ([64Cu][Cu(ES)]) as ... -
In vitro modelling of androgen-mediated gene-directed enzyme prodrug therapy for the treatment of prostate cancer
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Radiation Therapy, 2012)Gene-directed enzyme prodrug therapy has the potential to improve prostate cancer therapy outcome and could be used on its own or as an adjuvant to the current treatments. This research involved the characterisation of a ... -
Introduction to the ESTRO European Qualifications Framework (EQF) 7 and 8: Benchmarking Radiation Therapist (RTT) advanced education
(2018)Innovations in radiotherapy practice continue to develop and expand. With this comes a requirement for suitably educated Radiation TherapisTs (RTTs) to expand their scope of practice and work at advanced levels within ... -
Investigating the Needs and Concerns of Lesbian, Gay, Bisexual, Transgender, Queer, or Questioning Cancer Patients
(2024)The needs and concerns of lesbian, gay, bisexual, transgender, queer, or questioning (LGBTQ+) patients with cancer remain poorly understood. This is important as LGBTQ+ patients have an elevated risk of developing certain ... -
A joint physics and radiobiology DREAM team vision – Towards better response prediction models to advance radiotherapy
(2024)Radiotherapy developed empirically through experience balancing tumour control and normal tissue toxicities. Early simple mathematical models formalized this practical knowledge and enabled effective cancer treatment to ... -
Magnetic Resonance Imaging Radiomics - Towards the Personalisation of Radiation Therapy for Prostate Cancer.
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2020)The primary function of a predictive biomarker is to accurately determine the outcome of a specified treatment. Radiomics is a developing field that involves advanced image analysis and high throughput extraction of ...
