Browsing Physiology by Sponsor "National Institutes of Health (NIH)"
Now showing items 1-3 of 3
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Androgen receptor signaling in prostate cancer development and progression
(Carcinogenesis Press, 2011)The androgen receptor (AR) signaling axis plays a critical role in the development, function and homeostasis of the prostate. The classical action of AR is to regulate gene transcriptional processes via AR nuclear ... -
The impact of aging on the brain - risk, resilience and repair
(2012)This Brief Commentary describes a Special Issue that features a series of papers that provide new data on how aging and inflammation interact to affect behaviors that are regulated by the dialogue between the immune system ... -
SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis.
(2008)Peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator-1alpha (PGC-1alpha) is a highly regulated transcriptional coactivator that coordinates energy metabolism in mammals. Misregulation of PGC-1alpha has ...
