Browsing Psychiatry by Sponsor "Irish Research Council (IRC)"
Now showing items 1-4 of 4
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Age-related hearing loss and neurocognitive function: Normal and pathological processes in cognitive ageing
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2018)This thesis investigates age-related hearing loss (ARHL) as a potential biomarker and risk factor for cognitive decline and dementia. Two reviews were conducted to examine the evidence for an association in the epidemiological ... -
Investigation of α-tubulins as translational biomarkers of major depressive disorder: indications for disease severity and treatment efficacy
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2020)Introduction: Major Depressive Disorder is a significant cause of disability worldwide. In a 2017 report, the World Health Organisation estimated that 320 million people suffered from depression globally. Although several ... -
Rett syndrome and Fragile X: different etiology with common molecular dysfunctions
(2021)Rett syndrome (RTT) and Fragile X syndrome (FXS) are two monogenetic neurodevelopmental disorders with complex clinical presentations. RTT is caused by mutations in the Methyl-CpG binding protein 2 gene (MECP2) altering ... -
Rett syndrome in Ireland: a demographic study.
(2024)Background: Rett syndrome (RTT) is a rare neurodevelopmental condition associated with mutations in the gene coding for the methyl-CpG-binding protein 2 (MECP2). It is primarily observed in girls and affects individuals ...
