School of Medicine: Recent submissions
Now showing items 561-580 of 3444
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Oral symptom assessment tools in patients with advanced cancer: a scoping review
(2022)Purpose: Oral symptoms are common in patients with advanced cancer. The aim of this scoping review was to identify oral symptom assessment tools that have been specifically utilised in patients with "advanced cancer". Methods: ... -
MASCC/ISOO expert opinion on the management of oral problems in patients with advanced cancer
(2022)Purpose: The Palliative Care Study Group in conjunction with the Oral Care Study Group of the Multinational Association for Supportive Care in Cancer (MASCC) formed a sub-group to develop evidence-based guidance on the ... -
Multinational Association of Supportive Care in Cancer (MASCC) expert opinion/guidance on the use of clinically assisted nutrition in patients with advanced cancer
(2022)Purpose: The pro vision of clinically assisted nutrition (CAN) in patients with advanced cancer is controversial, and there is a paucity of specific guidance, and so a diversity in clinical practice. Consequently, the ... -
Palliative care in the era of novel oncological interventions: needs some �tweaking�
(2022)Cancer treatment has evolved enormously over the last 20 years, with developments in surgery, radiotherapy, chemo- therapy, targeted therapy, and immunotherapy. As a result, many cancer patients have improved outcomes ... -
A prospective, real-world, multinational study of naloxegol for patients with cancer pain diagnosed with opioid-induced constipation - the NACASY Study
(2022)The Naloxegol Cancer Study (NACASY) was a multinational European study aimed to evaluate the 4-week safety and efficacy of naloxegol in a real-world setting in patients with cancer pain diagnosed with opioid-induced ... -
Fidelity of Interventions to Reduce or Prevent Stress and/or Anxiety from Pregnancy up to Two Years Postpartum: A Systematic Review
(2021)Introduction Intervention fidelity refers to whether an intervention is delivered as intended and can enhance interpretation of trial outcomes. Fidelity of interventions to reduce or prevent stress and anxiety during ... -
Deep Learning Retinal Image Analysis for the Detection of CKD and Cardiovascular Risk Factors in the General Population
(2022)Background: Retinal blood vessel patterns provide an opportunity to personalize an individuals risk assessment for CKD and cardiovascular risk factors (CVRF). In this study we propose a deep learning (DL) based prediction ... -
Shining on others, I burn myself: time to disagree with Hippocrates
(2022)After 2 years of varying forms of lockdown, working (mostly) from home or under intense pressure, we have returned to in-person meetings. Yet, this transition was more intense and demanding than we considered. Yet is ... -
Stand Up, Speak Out! Racial Justice in Healthcare Education: Experiences of Minoritised Ethnic Students
(TCD, 2022)Funded by Trinity Equality Fund 2022, the Faculty of Health Sciences Equality, Diversity and Inclusion (EDI) Group and Immigrant Council of Ireland launched a project entitled ‘Stand Up, Speak Out! Racial Justice in ... -
BRAIN: Brain Injury in Neonates
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)Despite advances in neonatal care leading to a dramatic reduction in mortality rates in recent decades, there have been comparatively modest improvements in neurodevelopmental outcomes for infants born with neonatal ... -
C-reactive protein as a prognostic factor in cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2022)Prognostication, the prediction of future outcomes, is a key aspect of cancer care but remains imprecise. An elevated serum C-reactive protein (CRP) is associated with high symptom burden, poor quality of life and shorter ... -
Mental Disorders in Older Adults Admitted to General Hospitals: Review of Patient, Service Provision and Environmental Factors
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)The prevalence of mental illnesses in older general hospital inpatients has been studied widely however data from the Irish population is lacking. Psychiatry of Old Age Liaison (`POA Liaison¿) services provide assessment ... -
Can a practice pharmacist improve prescribing safety and reduce costs in polypharmacy patients? A pilot study on an intervention in an Irish general practice setting
(2022)Objectives: This study aimed to develop and assess the feasibility and cost impact of an intervention involving a practice pharmacist embedded in general practice to improve prescribing safety, deprescribe where appropriate ... -
The effectiveness of smoking cessation interventions for socio-economically disadvantaged women: A systematic review and meta-analysis
(2022)Introduction This systematic review and meta-analysis assessed the effectiveness of smoking cessation interventions among women smokers in low socio-economic status (SES) groups or women living in disadvantaged areas ... -
Health Technology Assessment of CD19 CAR T-Cell Therapies in the Irish Healthcare Setting.
(Trinity College Dublin. School of Medicine. Discipline of Pharmacology & Therapeutics, 2022)The aim of this research was to undertake health technology assessments of CD19 CAR T-cell therapies, tisagenlecleucel and axicabtagene ciloleucel. A bespoke cost-utility model was developed to examine the cost effectiveness ... -
A detailed comparison of Functional Threshold Power (FTP) versus Blood Lactate Thresholds, Ventilatory Threshold and Critical Power, proceeded by a trained model for FTP using GxT data
(Trinity College Dublin. School of Medicine. Discipline of Anatomy, 2022)The role of the power-based cycling test called the Functional Threshold Power test (FTP) is examined in the current research project. The computed cycling FTP (c-FTP) is reported to represent the uppermost power output ... -
'Toothless - the absence of political priority for oral health: a case study of Ireland 1994¿2021
(2022)Background Calls are emerging for oral health system reform under the Universal Healthcare (UHC) domain, while internationally there is an absence of political priority for oral health. In the Republic of Ireland there ... -
Investigation of retinal thickness using optical coherence tomography: a prospective phenotype study of patients with inherited ataxia
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Inherited cerebellar ataxias (CA) are clinically and genetically heterogeneous disorders. A diverse range of ophthalmic abnormalities have been reported in different subtypes of CA and, although visual symptoms are not ... -
Investigating the Role of Altered Energy Metabolism in the Therapeutic Response of Rectal Cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2022)Colorectal cancer (CRC) is the 3rd most commonly diagnosed cancer world-wide, accounting for an estimated 10% of all cancers diagnosed annually globally. One in three CRCs occur in the rectum. The standard of care for ... -
Development of a Frailty Index in the Irish Hip Fracture Database
(2022)Introduction In older people, hip fracture can lead to adverse outcomes. Frailty, capturing biological age and vulnerability to stressors, can indicate those at higher risk. We derived a frailty index (FI) in the Irish ...
