School of Medicine: Recent submissions
Now showing items 581-600 of 3444
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A stakeholders perspective on the 'kickstart to recovery' football programme in a community mental health service
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2022)Introduction: One in four Irish people will experience mental health difficulties. Those with mental illness often don t receive best practice physical healthcare due to the division between service areas in Ireland and ... -
Consensus for experimental design in electromyography (CEDE) project: Terminology matrix
(2021)Consensus on the definition of common terms in electromyography (EMG) research promotes consistency in the EMG literature and facilitates the integration of research across the field. This paper presents a matrix developed ... -
Using Explainable AI (XAI) for the prediction of falls in the older population
(2022)The prevention of falls in older people requires the identification of the most important risk factors. Frailty is associated with risk of falls, but not all falls are of the same nature. In this work, we utilised data ... -
Early Intervention in Psychosis services: a systematic review and narrative synthesis of the barriers and facilitators to implementation
(2021)Background Early intervention in psychosis (EIP) services target the early manifestation of psychosis and provide multidisciplinary care. They demonstrate effectiveness and cost-effectiveness. Implementation of EIP ... -
Non-adherence to COVID-19 containment behaviours: results from an all-Ireland telephone surv
(2022)Background COVID-19 public health measures like handwashing and social distancing can help stem the spread of the virus. Adherence to guidelines varies between individuals. This study aims to identify predictors of ... -
The Molecular Mechanisms of rhIGF1 in the Treatment of Rett Syndrome and Related Disorders: Studies in Patients, Mouse and Cellular Models
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)Recombinant human Insulin-like Growth Factor 1 (rhIGF1) is an approved treatment for growth failure and IGF1 deficiency. IGF1 has multiple functions in the body including growth, cell survival, metabolism, ageing and ... -
A process evaluation of ?We Can Quit? a community-based smoking cessation intervention targeting women from areas of socio-disadvantage in Ireland.
(2022)Background: Smoking poses a serious risk of early preventable death and disease especially for women living with socio-economic disadvantage (SED). A smoking cessation programme, ‘We Can Quit’, was developed in Ireland ... -
A cluster-randomised crossover pilot feasibility study of a multicomponent intervention to reduce occupational sedentary behaviour in professional male employees
(2021)Professional male office employees have been identified as those most at risk of prolonged sedentary time, which is associated with many long-term adverse health conditions. The aim of the study was to assess the acceptability ... -
Bordering on crisis: A qualitative analysis of focus group, social media, and news media perspectives on the Republic of Ireland-Northern Ireland border during the ?first wave? of the COVID-19 pandemic
(2021)Rationale International border controls were among the earliest and most effective of measures to constrain transmission of COVID-19. However, such measures are complex when established borders are open yet politically ... -
Prospective Study of a Novel Diagnostic Algorithm for Investigating and Managing Gastrointestinal Disease Through The Appropriate Use of Biomarkers and Wireless Based Capsule Endoscopy
This chapter gives a general outline of the thesis for better understanding of issues surrounding research areas and studies that have been performed. Lower Gastrointestinal (GI) Symptoms are common and often warrant further ... -
DRNI Survey Data
(Dementia Research Network Ireland (DRNI), 2022) -
The Plasticity of Neutrophil Subsets in Inflammation
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Neutrophils are a vital component of the innate immune system and the body s first line of defense against invading pathogens. The classic view of these cells is that they are a homogenous population of terminally ... -
Investigation of the role of sleep and physical activity risk for chronic disease prevalence in older Irish adults
(2022)Background: Chronic diseases are the leading cause of death worldwide. Many of these diseases have modifiable risk factors, including physical activity and sleep, and may be preventable. This study investigated independent ... -
The prediction of mortality from continuous noninvasive cardiovascular signals on standing: entropy was significant, but not the overall response profile
(2022)In this study, a novel approach is presented using principal component analysis and sample entropy (SampEn) for the analysis of continuous blood pressure (BP) data measured non-invasively during an active stand (AS) in ... -
12 weeks of simulated barefoot running changes foot-strike patterns in female runners
(2014)To investigate the effect of a transition program of simulated barefoot running (SBR) on running kinematics and foot-strike patterns, female recreational athletes (n=9, age 29 ± 3 yrs) without SBR experience gradually ... -
Ancestral Legacies of an Insular Archipelago: A genomic exploration of prehistoric Japan and mainland Asia
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)The objective of this thesis is to use ancient genomic data and a variety of bioinformatic approaches to explore human evolutionary history in the Japanese archipelago and mainland Asia. This thesis presents a dense genomic ... -
Transitions between degrees of multidimensional frailty among older people admitted to intermediate care: a multicentre prospective study
(2022)Background: Frailty is a dynamic condition that is clinically expected to change in older individuals during and around admission to an intermediate care (IC) facility. We aimed to characterize transitions between degrees ... -
Examining the role of lymphocytes in health and in neonatal encephalopathy and the influence of mucosal associated T cells on B cell functions
(Trinity College Dublin. School of Medicine. Discipline of Immunology, 2022)Background. Neonatal encephalopathy (NE) is a neurological syndrome in term babies characterised by altered levels of consciousness, seizures, abnormal tone and reflexes, and/or failure to initiate or maintain respiration. ... -
Is the FTP Test a Reliable, Reproducible and Functional Assessment Tool in Highly-Trained Athletes?
(2019)The aim of the current study was to assess reliability of the Functional Threshold Power test (FTP) and the corresponding intensity sustainable for 1-hour in a "quasi-steady state". Highly-trained athletes (n = 19) completed ... -
Efficacy of resistance training during adjuvant chemotherapy and radiation therapy in cancer care: a systematic review and meta-analysis
(2022)Purpose: To determine the effect of resistance training during adjuvant chemotherapy and radiation therapy in cancer patients on measures of lean mass and muscle strength. Secondary aims were to analyse the prescription ...