School of Medicine: Recent submissions
Now showing items 941-960 of 3444
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Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement.
(2010)Background: Total knee replacement has been demonstrated to be one of the most successful procedures in the treatment of osteoarthritis. However quadriceps weakness and reductions in function are commonly reported following ... -
Objective Sleep Duration in Older Adults: Results From The Irish Longitudinal Study on Ageing
(Wiley, 2020)Objective: This study assessed the distribution and correlates of objective sleep duration in the older population in Ireland. Design: Cross-sectional study using population-derived data from wave 3 of The Irish Longitudinal ... -
Functional exercise after total hip replacement (FEATHER) a randomised control trial.
(BMC Musculoskeletal Disorders 2012, 2012)Background: Prolonged physical impairments in range of movement, postural stability and walking speed are commonly reported following total hip replacement (THR). It is unclear from the current body of evidence what kind ... -
2020 international consensus on ANCA testing beyond systemic vasculitis
(2020)This document follows up on a 2017 revised international consensus on anti-neutrophil cytoplasm antibodies (ANCA) testing in granulomatosis with polyangiitis and microscopic polyangiitis and focuses on the clinical and ... -
Sphingosine-1-phosphate receptor modulator FTY720 attenuates experimental myeloperoxidase-ANCA vasculitis in a T cell-dependent manner
(2020)Sphingosine-1-phosphate (S1P) is a pleiotropic lysosphingolipid derived from the metabolism of plasma membrane lipids. The interaction between S1P and its ubiquitously expressed G-protein-coupled receptors (S1PR1-5) is ... -
Pro-inflammatory Stimulation of Monocytes by ANCA Is Linked to Changes in Cellular Metabolism
(2020)Clinical and experimental data suggest that pathogenesis in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is driven by ANCA-mediated activation of neutrophils and monocytes. While the role of neutrophils ... -
Altered lives in a time of crisis: The impact of the COVID-19 pandemic on the lives of older adults in Ireland. Findings from The Irish Longitudinal Study on Ageing
(TILDA, 2021)The ongoing pandemic of SARS-CoV-2, a novel coronavirus that causes COVID-19 infection and disease, is threatening healthcare systems globally as well as in Ireland. (1) The COVID-19 pandemic, and public health-associated ... -
Perceived stress before and during the COVID-19 pandemic
(2020)Since the beginning of the COVID-19 pandemic, perceived stress has increased significantly among older adults. This increase will likely negatively affect both physical and psychological wellbeing among this population. ... -
Older adults' experience of ageism during the COVID-19 pandemic
(TILDA, 2020)Despite the fact that the vast majority of older adults are not physically, cognitively or mentally impaired, age-related stereotypes persist. These stereotypes commonly portray older adults as physically and cognitively ... -
Preparing for COVID-19 vaccination: important learnings from the Irish Longitudinal Study on Ageing (TILDA)
(TILDA, 2020)This report brings together important information on vaccinations among adults aged 60 years and older learned from the Irish Longitudinal Study on Ageing (TILDA), which can inform the rollout of COVID-19 vaccinations. The ... -
Older adults shielding at home
(TILDA, 2020)Two thirds of adults aged 60 and older agreed or strongly agreed with shielding. Interestingly, a higher percentage of those most affected by policy, the over 70s, agreed with it. Whether people lived alone or with others ... -
Standardized Mortality Ratios in Homeless Populations in Dublin
(2019)Objective: To calculate standardised mortality ratios (SMRs) for a cohort of homeless people in the Dublin region over a 5-year period and to examine leading causes of death. Setting: Homeless services reporting deaths ... -
A naturalistic longitudinal analysis of post-detoxification outcomes in opioid-dependent patients.
(2018)Introduction and aims: To provide an assessment of outcomes in a cohort of opioid-dependent patients post-detoxification. Design and methods: This study employed an observational longitudinal cohort design. Patients who ... -
A Peer-Led Survey of Student Alcohol Behaviours and Attitudes in Undergraduate Students
(2021)Background: This study examines Irish undergraduate students’ behaviours and motives regarding alcohol consumption. The study explores both levels and patterns of consumption. Method: A cross-sectional design using a ... -
An audit of the cervical screening programme in the National Drug Treatment Centre (NDTC)
(2021)Background: Women diagnosed with substance use disorders (SUDs) have higher rates of major medical conditions compared to women without SUDs. Cervical cancer is the second leading cause of cancer death in women aged 20-39 ... -
New self-reported exhaustion during the COVID-19 Pandemic
(2021)In 2020, participants from The Irish Longitudinal Study on Ageing were surveyed to provide vital and timely information on lived experiences of older adults during the SARS-CoV-2 pandemic. During 2020, older adults experienced ... -
PICLS Staff Manual
(Prison Inreach & Court Liaison Service, NFMHS Central Mental Hospital, 2017) -
An examination of the neuroimmune interactions of amitriptyline, spinal cord stimulation and opioid therapy in human neuropathic pain
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2021)Background: The objective of this thesis was to explore mechanistic processes of amitriptyline, opioids and "Burst" spinal cord stimulation (SCS) for neuropathic pain in vivo. These three therapies are commonly employed ... -
Elucidating the complex organization of neural micro-domains in the locust Schistocerca gregaria using dMRI
(2021)To understand brain function it is necessary to characterize both the underlying structural connectivity between neurons and the physiological integrity of these connections. Previous research exploring insect brain ... -
Investigating clinically relevant phenotypes of neurodevelopmental copy number variants in Children and Adults
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2021)Background: Neurodevelopmental copy number variants (ND CNVs) present with clinically pleiotropic effects, transcending psychiatric diagnostic borders. Gaining clarity on the neurodevelopmental and psychiatric phenotypic ...
