Browsing Anatomy by Title
Now showing items 1-20 of 93
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12 weeks of simulated barefoot running changes foot-strike patterns in female runners
(2014)To investigate the effect of a transition program of simulated barefoot running (SBR) on running kinematics and foot-strike patterns, female recreational athletes (n=9, age 29 ± 3 yrs) without SBR experience gradually ... -
Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients
(2023)Tumour acidosis contributes to cancer progression by inhibiting anti-tumour immunity. However, the effect of acidosis on anti-tumour T cell phenotypes in oesophageal adenocarcinoma (OAC) is unknown. Therefore, this study ... -
Analysing the Combined Effects of Radiotherapy and Chemokine Receptor 5 Antagonism: Complementary Approaches to Promote T Cell Function and Migration in Oesophageal Adenocarcinoma.
(2024)The presence of an immunosuppressive tumour microenvironment in oesophageal adenocarcinoma (OAC) is a major contributor to poor responses. Novel treatment strategies are required to supplement current regimens and improve ... -
Assessment of an electronic patient record system on discharge prescribing errors in a Tertiary University Hospital
(2021)Background: Prescribing error represent a significant source of preventable harm to patients. Prescribing errors at discharge, including omission of pre-admission medications (PAM), are particularly harmful as they frequently ... -
A cadaveric dissection study of the anatomical variations of the ureter and implications for surgical intervention
(Trinity College Dublin. School of Medicine. Discipline of Anatomy, 2019)A cadaveric dissection study of the anatomical variations of the ureter and implications for surgical intervention Joan M. Costelloe The importance of studying ureteric anatomy such that it can be applied to surgical ... -
Challenging times: Delivering gene therapies and an opportunity for shared learning
(2021)As we embrace the era of precision medicine, gene therapies are the vanguard in the fight to cure rare diseases. While rare diseases are just that, rare, it is suggested that patients with rare diseases worldwide outnumber ... -
Characterisation of the effects of pulsed radio frequency treatment of the dorsal root ganglion on cerebrospinal fluid cellular and peptide constituents in patients with chronic radicular pain: a randomised, triple-blinded controlled trial
(2020)Introduction: Chronic radicular neuropathic pain is a major clinical problem with a life time prevalence of more than 50%. Pulsed radiofrequency (PRF) treatment is a recognised therapy. However, the pathophysiology of ... -
Chemokine-targeted therapies: An opportunity to remodel immune profiles in gastro-oesophageal tumours
(2021)Immunotherapies are transforming outcomes for many cancer patients and are quickly becoming the fourth pillar of cancer therapy. However, their efficacy of only ∼25% in gastro-oesophageal cancer has been disappointing. ... -
Clinical characteristics of two groups commonly referred to an Irish hypertension service—patients with resistant hypertension and young adults with hypertension
(2022)Background: The management of hypertension is primarily performed in primary care settings in many health systems. However, two groups of patients often require specialist input: patients with resistant hypertension (RH) ...
