Medical Gerontology: Recent submissions
Now showing items 101-120 of 529
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Low vitamin B 12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4-year longitudinal study
(2021)This was a longitudinal study utilising the Irish Longitudinal Study on Ageing (n 3849 aged ≥ 50 years) and investigated the relationship between blood plasma folate and B 12 levels at baseline (wave 1) and incident ... -
Patterns in health service utilisation: Results from Wave 5 of The Irish Longitudinal Study on Ageing
(2020)The purpose of this report is to examine social and health care service utilisation among older adults in the latest available wave (i.e. Wave 5) of The Irish Longitudinal Study on Ageing (TILDA) – both community and ... -
Sleep duration, sleep problems and perceived stress are associated with hippocampal subfield volumes in later life: Findings from The Irish Longitudinal Study on Ageing (TILDA).
(2021)Study Objectives: This study examines the cross-sectional and 2-year follow-up relationships between sleep and stress and total hippocampal volume and hippocampal subfield volumes among older adults. Methods: Four hundred ... -
Orthostatic blood pressure variability is associated with lower visual contrast sensitivity function: Findings from the Irish Longitudinal Study on Aging.
(2019)Background: Hypertension is established to cause vascular end-organ damage. Other forms of dysregulated blood pressure (BP) behaviour, such as orthostatic hypotension have also been associated with cardiovascular (CV) events. ... -
Orthostatic hypertension as a risk factor for age-related macular degeneration: Evidence from the Irish longitudinal study on ageing.
(2018)Purpose: Age related macular degeneration (AMD) is a leading cause of irreversible visual loss in developed countries. It is associated with vascular risk factors including hypertension. Dysregulated blood pressure ... -
Comparisons of disease cluster patterns, prevalence and health factors in the USA, Canada, England and Ireland.
(2021)Background: Identification of those who are most at risk of developing specific patterns of disease across different populations is required for directing public health policy. Here, we contrast prevalence and patterns ... -
High-risk categories for COVID-19 and their distribution by county in Republic of Ireland-evidence from the TILDA study
(2020)Older persons and those with pre-existing chronic conditions are most likely to experience severe consequences from COVID-19. Because immune defences decline and chronic diseases rise with age, people aged 70 and older ... -
Sustaining an ageing population: the role of micronutrients in frailty and cognitive impairment
(2023)Age-related frailty and cognitive decline are complex multidimensional conditions that sign- ificantly impact the ability of older adults to sustain functional capacity and independence. While underlying causes remain ... -
Cognitive decline associated with anticholinergics,benzodiazepines and Z-drugs: Findings from The Irish Longitudinal Study on Ageing (TILDA)
(2020)Aims: To estimate the association between patterns of anticholinergic, benzodiazepine and Z-drug medication use and change in cognitive function in middle-aged and older adults. Methods: This prospective cohort study ... -
Aspirin prescribing for cardiovascular disease in middle-aged and older adults in Ireland: Findings from The Irish Longitudinal Study on Ageing
(2021)Aspirin use for cardiovascular indications is widespread despite evidence not supporting use in patients without cardiovascular disease (CVD). This study characterises aspirin prescribing among people aged ≥50 years in ... -
Comparing Potentially Inappropriate Prescribing Tools and Their Association With Patient Outcomes
(2020)OBJECTIVE: To assess the agreement of several different measures of potentially inappropriate prescribing (PIP) in older people and compare their relationship with patient- reported outcomes. DESIGN: Prospective cohort ... -
Potentially inappropriate prescribing according to STOPP and START and adverse outcomes in community-dwelling older people: a prospective cohort study
(2016)AIMS: This study aims to determine if potentially inappropriate prescribing (PIP) is associated with increased healthcare utilization, functional decline and reduced quality of life (QoL) in a community-dwelling older ... -
Supine hypertension is associated with an impaired cerebral oxygenation response to orthostasis: Findings from the Irish Longitudinal Study on Ageing (TILDA)
(2021)The cerebrovascular effects of supine hypertension (SH) are still poorly understood. With aging and atherosclerosis of the vascular system, it is not uncommon for SH and non-neurogenic orthostatic hypotension to co-occur. ... -
Age and sex related differences in orthostatic cerebral oxygenation: Findings from 2764 older adults in the Irish Longitudinal Study on Ageing (TILDA).
(2022)Aims: Cerebral hypoperfusion is implicated in the pathogenesis of associations between orthostatic hypotension and adverse outcome such as falls, cognitive impairment, depression, and mortality. Although the blood pressure ... -
Age and sex differences in frontal lobe cerebral oxygenation in older adults - normative values using novel, scalable technology: Findings from the Irish Longitudinal Study on Ageing (TILDA)
(2019)Aims: Near-infrared spectroscopy (NIRS) is a non-invasive, easy to apply, optical technology for measuring cerebral blood oxygenation, but there is lack of comprehensive population data to aid interpretation and clinical ... -
Intergenerational Social Mobility and Allostatic Load in Midlife and Older Ages: A Diagonal Reference Modeling Approach
(2023)Objectives: This study aims to understand the association of life-course intergenerational social mobility with allostatic load (AL) burden in midlife and older ages in Ireland. Methods: The study involved biological ... -
An investigation of what protective individual- and community-level factors are associated with life satisfaction in middle-aged and older family carers in Ireland.
(2023)Background: Family care plays an essential role in providing care in society. However, caring can cause stress, and mental and physical responses to caring vary widely. Different outcomes for carers may reflect different ... -
Caring in the time of COVID-19, longitudinal trends in well-being and mental health in carers in Ireland: Evidence from the Irish Longitudinal Study on Ageing (TILDA).
(2022)Background: The COVID-19 pandemic in 2020 resulted in the older population being asked to remain at home and avoid other people outside their household. This could have implications for both receipt and provision of informal ... -
Stressful Life Events and Orthostatic Blood Pressure Recovery in Older Adults
(2015)Objective: The majority of the literature on stress and blood pressure (BP) concerns the increased risk of cardiovascular morbidity and mortality from high BP. Because the sympathetic nervous system is critical to the ...
