Medical Gerontology: Recent submissions
Now showing items 321-340 of 529
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Is orthostatic hypotension more common in individuals with atrial fibrillation? – Findings from The Irish Longitudinal Study on Ageing (TILDA)
(2017)Introduction: atrial fibrillation (AF) and orthostatic hypotension (OH) share common risk factors such as age, hypertension and cardiovascular (CV) disease. The autonomic nervous system (ANS) also plays a role in the ... -
Falls, non-accidental falls and syncope in community-dwelling adults aged 50 years and older: Implications for cardiovascular assessment
(2017)Objectives: To calculate the prevalence of all falls, non-accidental falls and syncope in an older population and characterize cardiovascular risk profiles. Design: Prospective, longitudinal cohort study. Setting: The ... -
Potentially inappropriate prescribing and its association with health outcomes in middle-Aged people: A prospective cohort study in Ireland
(2017)Objectives: To determine the prevalence of potentially inappropriate prescribing (PIP) in a cohort of community-dwelling middle-aged people and assess the relationship between PIP and emergency department (ED) visits, ... -
Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation
(2017)Low socioeconomic status (SES) is associated with earlier onset of age-related chronic conditions and reduced life-expectancy, but the underlying biomolecular mechanisms remain unclear. Evidence of DNA-methylation differences ... -
What Explains Socioeconomic Differences in the Speed of Heart Rate Recovery to Postural Challenge?
(2017)Background: Much recent work has focused on the value of heart rate recovery (HRR) as a marker of cardiovascular health and a predictor of mortality. This article explores socioeconomic variation in HRR following exposure ... -
Does baseline hypotension predict incident depression in a cohort of community-dwelling older people? Data from The Irish Longitudinal Study on Ageing (TILDA)
(2017)Background: hypotension is now recognised as a risk factor for syncope, cardiovascular events and mortality, but it may also represent a risk factor for late life depression (LLD). The aim of this study was to clarify ... -
The Association between Blood Pressure, Cerebral Perfusion and Late Life Depression
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2020)Background: While late life is generally characterised by contentment and happiness, depression in later life confers an independently increased risk of early mortality, cognitive and functional decline and nursing home ... -
Cardiovascular Autonomic Nervous System, Blood Pressure Instability and Brain Health in Older Adults: Population-Based Perspectives
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2019)The aim of this thesis is to provide new insights into the shared pathways by which the cardiovascular autonomic nervous system underpins optimal regulation of affect and cognitive function in older adults. Ageing is ... -
The frailty index in Europeans: association with age and mortality.
(2012)Background: the frailty index (FI) is an approach to the operationalisation of frailty based on accumulation of deficits. It has been less studied in Europeans. Objective: to construct sex-specific FIs from a large sample ... -
Vitamin D and orthostatic hypotension.
(2012)Introduction: we aimed to investigate on the potential relationship between vitamin D and orthostatic hypotension (OH) in a case-control model in older adults. Methods: all participants were community-dwelling adults who ... -
Change in perceived stress and 2-year change in cognitive function among older adults: The Irish Longitudinal Study on Ageing
(Wiley, 2018)Prolonged or severe stress can adversely affect older adults' cognitive function, but population‐based studies investigating this relationship over time are rare. Previous studies have largely focused on stress either ... -
Cohort Profile: the Irish Longitudinal Study on Ageing.
(2011)How did the study come about? Ireland shares with other developed countries the prospect of rapid and sustained population ageing. The age distribution of the Irish population is undergoing a dramatic change at present ... -
Summary of the Updated American Geriatrics Society/British Geriatrics Society Clinical Practice.
(2011)The following article is a summary of the American Geriatrics Society/British Geriatrics Society Clinical Practice Guideline for Prevention of Falls in Older Persons (2010). This article provides additional discussion ... -
Amnesia for loss of consciousness is common in vasovagal syncope.
(2011)The aim of this study was to determine the prevalence of amnesia for loss of consciousness (A-LOC) in those who have a history suggestive of vasovagal syncope (VVS) and who develop syncope on head-up tilt (HUT) table ... -
Comparison of centre and home-based health assessments: early experience from the Irish Longitudinal Study on Ageing (TILDA).
(2011)Background: some cohort studies of ageing and health supplement questionnaire-based surveys with in-home measurements of biological parameters and others have required respondents to attend assessment centres. Centre-based ... -
Loneliness, social isolation, and their discordance among older adults
(TILDA, 2019)We have shown here that loneliness and social isolation are not a necessary fact of the ageing process and recent efforts to alleviate these potentially damaging phenomena should be encouraged. This is particularly important ... -
Maternal educational inequalities in measured body mass index trajectories in three European countries
(2019)Background: Social inequalities in the prevalence of childhood overweight and obesity are well‐established, but less is known about when the social gradient first emerges and how it evolves across childhood and ... -
The effect of pregnancy intention on maternal prenatal behaviours and parent and child health: results of an Irish cohort study
(2013)Background: Unintended pregnancy is associated with increased risk for adverse neonatal and early childhood outcomes spanning an array of indicators, but it remains unclear whether these risks hold independent of other ... -
The Effects of Acute and Chronic Exercise on Brain Derived Neurotrophic Factor and Cognitive Performance in Mild Cognitive Impairment
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2019)Introduction: Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that supports neural survival, growth and synaptic plasticity and is upregulated through exercise. While the exact neuronal mechanisms underlying the ... -
Driving as a travel option for older adults: Findings from the Irish Longitudinal Study on Ageing
(2019)The role of transport in the health and wellbeing of older people is increasingly recognized: driving is the main form of personal transportation across the adult life-span. Patterns of changed mobility and driving cessation ...
