Medical Gerontology: Recent submissions
Now showing items 361-380 of 529
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Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis.
(2019)Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive to the accumulation of deleterious exposures across the ... -
Voluntary fortification is ineffective to maintain the vitamin B12 and folate status of older Irish adults: evidence from the Irish Longitudinal Study on Ageing (TILDA).
(2018)Mandatory fortification of staple grains with folic acid and/or vitamin B12 (B12) is under debate in many countries including Ireland, which has a liberal, but voluntary, fortification policy. Older adults can be at risk ... -
Hospitalisation and surgery: Are there hidden cognitive consequences? Evidence from The Irish Longitudinal study on Ageing (TILDA)
(2018)Background: the dramatic shift in the global population demographic has led to increasing numbers of older people undergoing hospitalisation and surgical procedures.Objectives:to determine whether hospitalisation or ... -
Mortality in relation to changes in a healthy aging index: The health, aging, and body composition study
(2019-04)Background: Baseline scores on a Healthy Aging Index (HAI), including five key physiologic domains, strongly predict health outcomes. This study aimed to characterize 9-year changes in a HAI and explore their relationship ... -
Dissociable age and memory relationships with hippocampal subfield volumes in vivo: Data from the Irish Longitudinal Study on Ageing (TILDA)
(2019)The heterogeneous specialisation of hippocampal subfields across memory functions has been widely shown in animal models. Yet, few in vivo studies in humans have explored correspondence between hippocampal subfield anatomy ... -
Control of HIV infection by IFN-α: implications for latency and a cure.
(Springer, 2018)Viral infections, including HIV, trigger the production of type I interferons (IFNs), which in turn, activate a signalling cascade that ultimately culminates with the expression of anti-viral proteins. Mounting evidence ... -
How does socio-economic position (SEP) get biologically embedded? A comparison of allostatic load and the epigenetic clock(s)
(Elsevier, 2019)Individuals of lower socio-economic position (SEP) carry a heavier burden of disease and morbidity and live shorter lives on average compared with their more advantaged counterparts. This has sparked research interest in ... -
Impact of assistance on the quality of life of older adults with activities of daily living & instrumental activities of daily living disabilities
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2018)As populations age, incidence of functional limitation including disability in Activities of Daily Living and Instrumental Activities of Daily Living increases. This creates a higher level of demand for technological and ... -
Cardiovascular associations of falls and syncope in the elderly
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2017)The principle aims of this doctoral investigation are to provide new insights into the relationship between cardiovascular disease (CVD) and falls in the elderly population in Ireland. The rapidly ageing global demographic ... -
Treatment of osteoporosis with recombinant parathyroid hormone, its effects on bone, total body muscle and fat composition and factors determining response to this therapy
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2015)Total body bone mineral density (BMD) is relatively underutilised as an assessment tool for osteoporosis. Studies to date on Body composition have not clearly identified key factors which contribute to total body BMD, ... -
Haemodynamic stroke and transient ischaemic attack secondary to neurocardiovascular instability
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2014)Introduction: Presyncope or syncope are regarded as benign conditions. In patients with severe large artery disease, hypotension may potentiate infarction, specifically in low-flow vulnerable, borderzone regions of the ... -
The influence of perceptions of ageing on frailty and cognitive function
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2015)The aim of this thesis is to investigate whether perceptions of ageing influence cognition and frailty in later life. Although much experimental work has shown that priming older adults with negative stereotypes about ... -
Autonomic influences on cognitive performance at a population level
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2014)The principle aims of this doctoral investigation were to provide new insights into the relationship between cardiovascular disease (CVD) and cognitive performance, by investigating the function of the autonomic nervous ... -
Health Insurance, Healthcare Utilisation and Screening
(TILDA, 2017)