Medical Gerontology: Recent submissions
Now showing items 381-400 of 529
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Aesthetic deprivation : the role of aesthetics for older patients in hospital
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2014)While arts have been integral to all cultures, it is a relatively recent research phenomenon to explore and examine the association between arts and health and well-being (Johnson and Stanley, 2007). This research centres ... -
Fear of falling in older adults
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2014)The principle aim of this doctoral investigation was to provide new insights into the prevalence, risk factors and negative associations of fear of falling (FOF) by examining these factors in a population sample of older adults. -
An investigation of the incidence of falling and risk factors for falls in adults with advanced cancer
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2012)The principal aims of this doctoral investigation were to identify the incidence of falls and risk factors for falling in adults with advanced cancer. -
Multiple medication use in the middle and older age population
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2013)Polypharmacy in the older population is increasingly common and can represent necessary preventative therapies or potential inappropriate prescribing and be a risk factor for falls. In addition, medications with anti-cholinergic ... -
Investigation of apraxia of speech and linguistic dysprosody following acute ischaemic hemispheral stroke
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2011)Apraxia of speech (AOS) is a disorder of motor speech programming. Affected patients typically have hesitant, groping speech with impaired prosody. Automatic speech is relatively well preserved compared to propositional ... -
Autonomic function and depression in older adults
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2013)The principle aims of this doctoral investigation were to provide new insights into the relationship between depression and cardiovascular disease (CVD) by investigating the functioning of the autonomic nervous system (ANS) ... -
Vasovagal Syncope in the older adult
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2013)Vasovagal Syncope (VVS) is a common form of neurally mediated syncope which affects at least one third of the population at least once in their lifetime. Commonly referred to as a “simple faint” and often described as ... -
An investigation of the safety, efficacy, and possible mechanisms of action, of the antihypertensive nilvadipine, in patients with mild moderate Alzheimer's disease
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2011)This doctoral investigation endeavoured to explore how patients with Alzheimer's disease (AD) would respond to treatment with the antihypertensive nilvadipine. Initially I reviewed the complex relationship between blood ... -
Analysis and biophysical modelling of baroreflex stimulation with applications in syncope and falls : a neural engineering approach
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2011)Carotid Sinus Hypersensitivity (CSH) is an age related disorder, and a common cause of recurrent falls and syncope in the elderly. CSH is prevalent in patients with Dementia and Parkinson's disease and is a strong predictor ... -
Autonomic influences on cognitive impairment : determinants of conversion to dementia
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2012)Neuropathological, neurochemical and multimodal neuroimaging studies suggest that components of the central autonomic network are affected by the neurodegenerative changes of Alzheimer’s pathology in Mild Cognitive Impairment ... -
European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease - The substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow
(2016)Introduction In conjunction with the NILVAD trial, a European Multicentre Double-Blind Placebo Controlled trial of Nilvadipine in Mild-to-Moderate Alzheimer's disease (AD), there are four NILVAD substudies in which eligible ... -
Safety and tolerability of Tilt Testing and Carotid Sinus Massage in the octogenarians
(2016)Objective: to evaluate the safety and tolerability of Tilt Testing (TT) and Carotid Sinus Massage (CSM) in octogenarians with unexplained syncope. Methods: patients consecutively referred for transient loss of consciousness ... -
Social disadvantage and social isolation are associated with a higher resting heart rate: evidence from The Irish Longitudinal Study on Ageing (TILDA)
(2015)OBJECTIVES: A high resting heart rate (RHR) represents a major risk factor for cardiovascular disease and individuals from poorer backgrounds have a higher RHR compared with their more advantaged peers. This study ... -
The effect of acute traumatic brain injury on cardiovascular homeostasis
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2008)Acute traumatic brain injury (TBI) remains the most common cause of death from multiple trauma. The cardiovascular homeostatic responses to haemorrhage and injury are co-coordinated in the central nervous system. Coincidental ... -
Adaptation to stroke and a model of successful ageing
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2008)The focus of this research is to apply and examine the Baltes’ successful ageing model of selection, optimization and compensation (SOC) (Baltes & Baltes, 1990) in the context of stroke which has sudden onset and uncertain ... -
Trail Making Test performance contributes to subjective judgment of visual efficiency in older adults
(PeerJ Inc., 2015)Introduction. The determinant factors that influence self-reported quality of vision have yet to be fully elucidated. This study evaluated a range of contextual information, established psychophysical tests, and in particular, ... -
Improving the efficiency of multisensory integration in older adults: audio-visual temporal discrimination training reduces the susceptibility to the sound-induced flash illusion.
(2014)From language to motor control, efficient integration of information from different sensory modalities is necessary for maintaining a coherent interaction with the environment. While a number of training studies have focused ... -
A Frailty Instrument for primary care for those aged 75 years or more: findings from the Survey of Health, Ageing and Retirement in Europe, a longitudinal population-based cohort study (SHARE-FI75+).
(2014)Objective To create and validate a frailty assessment tool for community-dwelling adults aged ≥75 years. Design Longitudinal, population-based study. Setting The Survey of Health, Ageing and Retirement in Europe ...
