RSS Feeds: Recent submissions
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Cytosolic dsRNA improves neonatal innate immune responses to adjuvants in use in paediatric vaccines.
(2022)Pattern recognition receptors (PRRs) of the innate immune system represent the critical front-line defense against pathogens, and new vaccine formulations target these PRR pathways to boost vaccine responses, through ... -
Minocycline suppresses disease-associated microglia (DAM) in a model of photoreceptor cell degeneration
(2022)As the resident immune cells in the retina, microglia play important homeostatic roles in retinal immune regulation and neuroprotection. However, chronic microglia activation is a common hallmark of many degenerative retinal ... -
SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration
(2022)SARM1 (sterile alpha and armadillo motif-containing protein) is a highly conserved Toll/IL-1 Receptor (TIR) adaptor with important roles in mediating immune responses. Studies in the brain have shown that SARM1 plays a ... -
Elastic FemtoCaching: Scale, Cache, and Route
(2021)The advent of elastic Content Delivery Networks (CDNs) enable Content Providers (CPs) to lease cache capacity on demand and at different cloud and edge locations in order to enhance the quality of their services. This ... -
Experimental Evaluation of Power Consumption in Virtualized Base Stations
(2021)Network virtualization is intended to be a key element of new generation networks. However, it is no clear how the implantation of this new paradigm will affect the power consumption of the network. To shed light on this ... -
Demonstrating a bayesian online learning for energy-aware resource orchestration in vRANs
(2021)Radio Access Network Virtualization (vRAN) will spearhead the quest towards supple radio stacks that adapt to heterogeneous infrastructure: from energy-constrained platforms deploying cells-on-wheels (e.g., drones) or ... -
Sympathy for the digital: influence of synthetic voice on affinity, social presence and empathy for photorealistic virtual humans
(2022)In this paper, we investigate the effect of a realism mismatch in the voice and appearance of a photorealistic virtual character in both immersive and screen-mediated virtual contexts. While many studies have investigated ... -
Microstructure and tribological properties of Al2O3 reinforced FeCoNiCrMn high entropy alloy composite coatings by cold spray
(2022)High entropy alloys (HEAs) are novel materials that have been extensively studied in recent years. In this work, Al2O3 particles reinforced FeCoNiCrMn HEA composite coatings were fabricated by cold spray. The microstructure, ... -
Improvement of tensile strength of cold sprayed Fe deposits via in-process powder preheating
(2022)Cold sprayed Fe deposits were manufactured with non-preheated and preheated powders, respectively. The microstructure of the deposits was characterized by electron backscattered diffraction. The tensile property of the ... -
How to train your dog: Neural enhancement of quadruped animations
(2021)Creating realistic quadruped animations is challenging. Producing realistic animations using methods such as key-framing is time consuming and requires much artistic expertise. Alternatively, motion capture methods have ... -
Influence of processing parameters on density, surface morphologies and hardness of as-built Ti-5Al-5Mo-5V-3Cr alloy manufactured by selective laser melting
(2022)Demand for new Ti alloys for AM is immense. Ti–5Al–5Mo–5V–3Cr (wt%), a β type Ti alloy is chosen for this study as it possesses excellent properties. Samples are manufactured using SLM technique. Relative density, surface ... -
Model for predicting perception of facial action unit activation using virtual humans
(2021)Blendshape facial rigs are used extensively in the industry for facial animation of virtual humans. However, storing and manipulating large numbers of facial meshes (blendshapes) is costly in terms of memory and computation ... -
Ascending from the valley: Can state-of-the-art photorealism avoid the uncanny?
(2021)Advancements in real-time rendering technology have continued to develop rapidly over the course of the last decade. Consequently, human likenesses have been represented virtually with increasingly impressive detail. ... -
No-Regret Slice Reservation Algorithms
(2021)Emerging network slicing markets promise to boost the utilization of expensive network resources and to unleash the potential of over-the-top services. Their success, however, is conditioned on the service providers (SPs) ... -
Potential Role of Flavivirus NS2B-NS3 Proteases in Viral Pathogenesis and Anti-flavivirus Drug Discovery Employing Animal Cells and Models: A Review
(2022)Flaviviruses are known to cause a variety of diseases in humans in different parts of the world. There are very limited numbers of antivirals to combat flavivirus infection, and therefore new drug targets must be explored. ... -
Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells
(2022)Coronaviruses (CoVs) have caused several global outbreaks with relatively high mortality rates, including Middle East Respiratory Syndrome coronavirus (MERS)-CoV, which emerged in 2012, and Severe Acute Respiratory Syndrome ... -
An overview of current knowledge of deadly covs and their interface with innate immunity
(2021)Coronaviruses are a large family of zoonotic RNA viruses, whose infection can lead to mild or lethal respiratory tract disease. Severe Acute Respiratory Syndrome-Coronavirus-1 (SARS-CoV-1) first emerged in Guangdong, China ... -
The high prevalence of asymptomatic SARS-CoV-2 infection reveals the silent spread of COVID-19
(2021)The COVID-19 pandemic has led to over 92 million cases and 1.9 million deaths worldwide since its outbreak. Public health responses have focused on identifying symptomatic individuals to halt spread. However, evidence ... -
Radical-mediated thiol–ene ‘click’ reactions in deep eutectic solvents for bioconjugation
(2022)Herein, we report the first application of deep eutectic solvents (DESs) in radical-mediated hydrothiolation reactions. Under UV and atmospheric-oxygen mediated conditions, the thiol–ene reac tion was applied to amino ... -
Neutrophils: Need for Standardized Nomenclature
(2021)Neutrophils are the most abundant innate immune cell with critical anti-microbial functions. Since the discovery of granulocytes at the end of the nineteenth century, the cells have been given many names including phagocytes, ...
