Browsing Dental Science by Date of Publication
Now showing items 1-20 of 241
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Candida dubliniensis: An update
(1999)The increased incidence of fungal infections during the last decade has been well-documented. Given that one of the most important factors contributing to this phenomenon is the increased numbers of immunocompromised ... -
An investigation into the molecular epidemiology of Candida dubliniensis
(Trinity College (Dublin, Ireland). School of Dental Science, 2002)Candida dubliniensis is a recently described Candida species primarily associated with oral candidosis in Human Immunodeficiency Virus (HlV)-infected and AIDS patients. The population structure of C. dubliniensis was ... -
Investigation into the molecular mechanisms of itraconazole resistance in Candida dubliniensis
(Trinity College (Dublin, Ireland). School of Dental Science, 2003)Candida dubliniensis is a recently identified yeast species primarily associated with oral carriage and infection in HIV-infected individuals. Previous studies have shown that only a small number of clinical isolates are ... -
COMPARATIVE GENOMICS USING CANDIDA ALBICANS DNA MICROARRAYS REVEALS ABSENCE AND DIVERGENCE OF VIRULENCE ASSOCIATED GENES IN CANDIDA DUBLINIENSIS
(2004)Candida dubliniensis is a pathogenic yeast species closely related to Candida albicans. However, it is less frequently associated with human disease and displays reduced virulence in animal models of infection. We have ... -
An investigation into the biofilm-associated bacterial contamination of dental chair units and dental unit output water supplies and its control
(Trinity College (Dublin, Ireland). School of Dental Science, 2005)Many modern medical devices, including dental chair units (DCUs), are potential reservoirs of infection as they can harbour biofilm-associated microorganisms. This study investigated several aspects of DCUs related to ... -
NOVEL 5-FLUCYTOSINE-RESISTANT CLADE OF CANDIDA DUBLINIENSIS FROM SAUDI ARABIA AND EGYPT IDENTIFIED BY CD25 FINGERPRINTING.
(2005)DNA fingerprinting of Candida dubliniensis isolates using the species-specific probe Cd25 previously showed that this species consists of two distinct groups, termed Cd25 group I and Cd25 group II. The present study ... -
Reduced azole susceptibility in genotype 3 C. dubliniensis isolates associated with increased CdCDR1 and CdCDR2 expression.
(2005)Candida dubliniensis is a recently identified yeast species primarily associated with oral carriage and infection in HIV-infected individuals. The species can be divided into at least four genotypes on the basis of the ... -
AZOLE SUSCEPTIBILITY AND RESISTANCE IN CANDIDA DUBLINIENSIS
(2005)Candida dubliniensis is a recently described species of pathogenic yeast that shares many phenotypic features with Candida albicans. It is primarily associated with oral colonization and infection in HIV-infected individuals. ... -
Lower filamentation rates of Candida dubliniensis contribute to its lower virulence in comparison with Candida albicans
(Elsevier, 2007)Candida albicans and Candida dubliniensis are very closely related yeast species. In this study, we have conducted a thorough comparison of the ability of the two species to produce hyphae and their virulence in two ... -
DIFFERENTIAL REGULATION OF THE TRANSCRIPTIONAL REPRESSOR NRG1 ACCOUNTS FOR ALTERED HOST CELL INTERACTIONS IN CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS
(2007)Candida dubliniensis is genetically closely related to C. albicans, but causes fewer infections in humans and exhibits reduced virulence and filamentation in animal models of infection. We investigated the role of the ... -
DIFFERENTIAL REGULATION OF THE TRANSCRIPTIONAL REPRESSOR NRG1 ACCOUNTS FOR ALTERED HOST CELL INTERACTIONS IN CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS
(Blackwell Publishing, 2007-09)Candida dubliniensis is genetically closely related to C. albicans, but causes fewer infections in humans and exhibits reduced virulence and filamentation in animal models of infection. We investigated the role of the C. ... -
MULTILOCUS SEQUENCE TYPING REVEALS THAT THE POPULATION STRUCTURE OF Candida dubliniensis IS SIGNIFICANTLY LESS DIVERGENT THAN THAT OF Candida albicans
(2008)he pathogenic yeast Candida dubliniensis is phylogenetically very closely related to Candida albicans, and both species share many phenotypic and genetic characteristics. DNA fingerprinting using the species-specific probe ... -
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
(2008)Abstract: Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually(1). To identify genetic factors that modify disease risk, we conducted a genome- wide association study by ... -
Multilocus sequence typing reveals that the population structure of Candida dubliniensis is significantly less divergent than that of Candida albicans.
(2008)The pathogenic yeast Candida dubliniensis is phylogenetically very closely related to Candida albicans, and both species share many phenotypic and genetic characteristics. DNA fingerprinting using the species-specific probe ... -
Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress
(Wiley-Blackwell, 2009)Candida albicans is more pathogenic than Candida dubliniensis. However, this disparity in virulence is surprising given the high level of sequence conservation and the wide range of phenotypic traits shared by these two ... -
The influence of pre-operative antibiotic administration on post-operative morbidity in dental implant placement
(Trinity College (Dublin, Ireland). School of Dental Science, 2009)The success of dental implants for the rehabilitation of both the partially and fully edentulous patient is well documented in the scientific literature. There are no clear guidelines on the use of prophylactic antibiotics ... -
A Ser29Leu SUBSTITUTION IN THE CYTOSINE DEAMINASE Fca1p IS RESPONSIBLE FOR CLADE-SPECIFIC 5-FLUCYTOSINE RESISTANCE IN Candida dubliniensis
(2009)The population structure of the opportunistic yeast pathogen Candida dubliniensis is composed of three main multilocus sequence typing clades (clades C1 to C3), and clade C3 predominantly consists of isolates from the ... -
Effect of surface contamination on re-osseointegration of dental implants surrounded by circumferential bone defects
(Trinity College (Dublin, Ireland). School of Dental Science, 2009)This study was designed to evaluate the effect of surface contamination on re-osseointegration of dental implants surrounded by circumferential bone defect and to compare osseointegration around Osseotite® implants (Biomet ... -
A clinical study to evaluate the success of two commercially available aesthetic stainless steel crowns on primary molars
(Trinity College (Dublin, Ireland). School of Dental Science, 2009)The aim of this study was to evaluate the clinical and radiographic success of two commercially available aesthetic stainless steel crowns on carious primary molars. The objectives were to compare the crown types to each ...
