Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 161-180 of 7000
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Exploring the Design of Conversational Agents for Mental Health Self-Monitoring
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2025)An enduring aspiration is to use conversational agents (CAs) to provide mental health support (MHS) in order to tackle the persistent mental health treatment gap. CAs are computer interfaces that interact with people in a ... -
Piezoresistance and Electrical Conduction in Solution-Processed 2D Nanosheet Networks
(Trinity College Dublin. School of Physics. Discipline of Physics, 2025)Nanosheet networks are attracting much interest as printed electronic devices, utilising the physical properties of 2D nanosheets. Electrical conduction and the impact of strain on conduction in the networks is of ... -
Supporting clinicians in the decision of including or excluding PGHD for the clinical decision process.
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2025)The integration of Patient-Generated Health Data (PGHD) into clinical decision-making holds immense potential for enhancing personalized healthcare. However, trust remains a critical barrier to its widespread adoption by ... -
How do Parental Resources affect Child-wellbeing? Evidence from birth cohort studies
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Sociology, 2025)This thesis examines the complex relationship between parental resources and child well-being, using high-quality longitudinal data from large-scale birth cohort studies in Ireland, Australia, and the United Kingdom. It ... -
The Acceptability and Usability of Outcome Measures for Social Prescribing Services
(Trinity College Dublin. School of Medicine. Discipline of Paediatrics, 2025)Background: Social prescribing has gained momentum within healthcare systems globally, bridging the gap between medical and non-medical services. It offers significant benefits, particularly in improving mental health and ... -
From Vagina Monologues to "Bloody Brides" and Back Again: Vaginal Myths, Street Politics, and Migrant Textile Theatrical Labour in Chinese Feminist Performances (2000s-2020s)
(Trinity College Dublin. School of Creative Arts. Discipline of Drama, 2025)This PhD thesis seeks to explore the ways in which contemporary feminism in China has been enacted and embodied, examining the emergence of new feminist subjects forged by these evolving practices. Central to this inquiry ... -
The Wind-Induced Vibration Response of Modular High-Rise Buildings
(Trinity College Dublin. School of Engineering. Disc of Civil Structural & Environmental Eng, The School of Engineering, 2025)Structural engineering continues to advance and push boundaries enabling taller, more slender and flexible structures to be realised. However, these structures are often more susceptible to significant wind-induced ... -
Using Personalisation to Tackle Misinformation and Disinformation on Social Media
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2025)Social media�s ubiquity in contemporary society is undeniable, serving as a crucial platform for communication, information sharing, and community building. However, this digital landscape is fraught with misinformation�false ... -
Corporate Risk Culture, Governance and Foreign Exchange Risk Management
(Trinity College Dublin. School of Business. Discipline of Business & Administrative Studies, 2025)This thesis investigates the influence of corporate risk culture and corporate governance on firm-level foreign exchange (FX, hereafter) rate risk management. This thesis adopts a three-essay format to explore how managerial ... -
Essays in Behavioral and Financial Economics
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Economics, 2025)This thesis consists of three essays on behavioral and financial economics. Each chapter provides insights into how consumers interact with various financial products, and offers policy recommendations related to consumer ... -
Investigation of Static & Active Structural Colouration in Ultrathin Film Lossy Fabry-Perot Resonator Stack Structures
(Trinity College Dublin. School of Physics. Discipline of Physics, 2025)The main aim of the research laid out in this work is to characterise the optical response of high index lossy absorbers like MoS2, Si, Ge, VO2, and Nio in various all-thin-film Fabry-Perot wave interference nanocavity ... -
I'm A Loser, Baby: An Analysis of Party Responsiveness to Vote Loss
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Political Science, 2025)Understanding how parties change is fundamental to understanding their role in representative democracy, and the alternatives that are available to voters. In particular, understanding how they change in response to election ... -
The optimisation of a preselection methodology of heterotypic spheroids for the in vitro investigation of angiogenesis in lung cancer.
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Lung cancer, particularly non-small cell lung cancer (NSCLC), is a leading cause of cancer-related deaths. Angiogenesis, the formation of new blood vessels, is essential for disease progression. The tumour microenvironment ... -
MEDICINAL CHEMISTRY STUDIES ON DIANHYDROHEXITOLS AS SCAFFOLDS FOR NOVEL ANTI-INFLAMMATORY DRUG DESIGN
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2025)This thesis focuses on the design, synthesis, and evaluation of novel anti‐inflammatory compounds using dianhydrohexitol scaffolds. The primary aim was to develop more potent alternatives to the lead compound, ST0702, ... -
Beneath the Surface: Mathematical Perspectives on Flows Generated by Submarine Volcanic Eruption in Stratified Oceans.
(Trinity College Dublin. School of Engineering. Disc of Civil Structural & Environmental Eng, 2025)This thesis addresses critical gaps in understanding the fluid dynamics generated by submarine volcanic eruptions in both shallow and deep ocean environments. The research utilizes a combination of analytical and numerical ... -
IFN-gamma-induced trained immunity as a strategy to enhance anti-microbial responses in human monocytes and macrophages.
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Infectious diseases remain a significant global health threat, exacerbated by the rise in multi-drug- resistant infections and the potential for epidemics. Mycobacterium tuberculosis (M.tb) and Staphylococcus aureus are ... -
Investigating the effects of TLR2/MyD88 deficiency in mouse models of age-related macular degeneration
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Age-related macular degeneration (AMD) is the leading cause of blindness among older populations. Despite its global prevalence, a definitive cure for AMD remains elusive. To tackle this, we are focused on modulating the ... -
Long-Term Use of Medications with Anticholinergic Activity in Older Adults with Intellectual Disability: Prescribing Challenges and Impact on Health Outcomes
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2025)Background: Older adults with intellectual disability are exposed to polypharmacy and a high anticholinergic burden due to the high prevalence of mental and neurological disorders. A cumulative anticholinergic burden has ... -
Cerebral haemodynamics in older adults: Multi-modal studies utilizing near infrared spectroscopy and non-invasive continuous blood pressure monitoring in a large longitudinal cohort
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, School of Medicine, Trinity College Dublin, 2025)Sufficient cerebral blood flow (CBF) is critical for brain health and normal cognitive function, and cerebral hypoperfusion is implicated as a pathway to cognitive decline, as well as other adverse outcomes such as falls, ... -
An Exploration of Cellular Signatures of Ageing, and the Effects of Age-Related Dysregulated Myeloid Circadian Rhythm in Retinal Disease.
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Age-related macular degeneration (AMD) is the most common cause of vision loss and blindness in the elderly population across the developed world. This disease is characterised by a gradual degeneration and death of ...
