Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 181-200 of 7000
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The Effect of Peripheral Nerve Stimulation on Implicit Motor Learning
(Trinity College Dublin. School of Psychology. Discipline of Psychology, 2025)Applying brain stimulation to motor learning and recovery has been a primary goal since the field was established. Using transcranial alternating current stimulation, electrical current is hypothesized to enter the brain ... -
Multi-Ethnic Communities and Religion: How Responsive are Irish Primary Schools to Cultural and Religious Diversity?
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Sociology, 2025)Ireland's cultural and religious identity has transformed considerably in the past three decades. Consequently, the primary school classroom has become an important platform in which to assist young people to develop the ... -
The Role of Incidental Experiences of Leader Identity for Leaders' Well-Being
(Trinity College Dublin. School of Business. Discipline of Business & Administrative Studies, 2025)This thesis focuses on the phenomenon of incidental leader identity as an understanding that incidental behaviors can shape leader identity. Three studies are presented that enhance our knowledge of incidental leader ... -
4-octyl itaconate and itaconate in the regulation of type I interferon in macrophages
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2025)Itaconate is an endogenous immunomodulatory metabolite produced by the enzyme aconitate decarboxylase 1 (ACOD1), a product of the gene immune-responsive gene 1 (Irg1). Itaconate is the most highly upregulated metabolite ... -
Governance Mechanisms and Corporate Green Bond Issuances
(Trinity College Dublin. School of Business. Discipline of Business & Administrative Studies, 2025)To reorient economies towards climate-resilient trajectories compatible with the goal of the Paris Agreement to limit the global temperature increase to 1.5 degrees Celsius, vast amounts of capital are needed to be ... -
The effect of a smartphone application self-management programme on clinical health outcomes in patients with Chronic Obstructive Pulmonary Disease: A feasibility randomised controlled trial
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2025)Background: Chronic Obstructive Pulmonary Disease (COPD) is an incurable disease that results in frequent exacerbations leading to regular hospitalisations among this cohort. Frequent exacerbations and hospitalisations can ... -
On The Relationship Between Freedom and Justice -- An Analysis of the Works of Ian Carter and John Rawls
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Political Science, 2025)This dissertation analyzes the relationship between freedom and justice. More specifically, this dissertation identifies two rivaling approaches to this relationship in the works of John Rawls and Ian Carter. The key ... -
Mechanisms, kinetics and pathways in the early-stage crystallisation of Ca-REE-F-bearing carbonates under ambient and hydrothermal conditions
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2025)The aim of this study is to investigate the reaction pathways, mechanisms, kinetics, and energetics of the REE-CaF2-CaCO3 system crystallization reactions. It also seeks to understand the role of different REEs in the ... -
Assessing the gait, physical activity and quality of life benefits of mobility assistance dogs for children with physical and neurological impairments
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2025)Children with physical and neurological impairments such as cerebral palsy often have difficulty walking. Reduced activity levels and participation restrictions in these children may lead to reduced quality of life, ... -
Associations between early-life behaviours, current oral health behaviours and oral health among children in Brunei Darussalam and the recommendations for oral health prevention strategies
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, School of Dental Science, 2025)Background: There is limited evidence of inequalities in dental caries in deciduous dentition among children in Brunei Darussalam. Moreover, there is no evidence assessing the associations of early-life behaviours and ... -
An investigation of spectroscopic diversity in the pre-peak regime of thermonuclear supernovae
(Trinity College Dublin. School of Physics. Discipline of Physics, 2025)As the most commonly found transient in the night sky due to their high intrinsic brightness, Type Ia supernovae (SNe Ia) have shown themselves to be powerful cosmological tools due to their standardisable nature. There ... -
Understanding the Impact of Metabolic Alterations on Brain Development
(Trinity College Dublin. School of Medicine. Discipline of Anatomy, 2025)Evaluating the metabolic requirements of neural stem cells, including the balance between glucose and ketone body utilisation, is important in understanding their role in brain development and disease. This study examined ... -
Cost and resource requirements for colorectal cancer screening in Ireland
(Trinity College Dublin. School of Medicine. Discipline of Public Health & Primary Care, 2025)Colorectal cancer (CRC) is a global public health problem. CRC screening reduces the colorectal cancer burden through the removal of precursor lesions and identifying the disease at an early stage. CRC screening is ... -
The Dance of Engagement: A Constructivist Grounded Theory Study of Parental Engagement.
(Trinity College Dublin. School of Linguistic Speech & Comm Sci. Discipline of Clin Speech & Language Studies, School of Linguistic, Speech and Language Studies, 2025)This thesis is focused on the process of effective parental engagement through the multiple perspectives of parents and practitioners in an area of socio-economic disadvantage. The potential positive impact of effective ... -
Bose condensation in nonequilibrium quantum gases: An adventure in the thermodynamics of light and matter
(Trinity College Dublin. School of Physics. Discipline of Physics, 2025)Nonequilibrium condensates in microcavities have been extensively analysed over the past decades. Like equilibrium condensates, they are characterised by a macroscopic population of the ground state, however, the system ... -
Synthesis and physicochemical analysis of pyrazinib and quininib prodrugs and discovery of novel cysteinyl leukotriene receptor 1 antagonists
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2025)Gastrointestinal cancers, particularly oesophageal adenocarcinoma (OAC), are aggressive diseases with a poor 5-year survival rate of less than 20%. Current treatment for OAC is neoadjuvant therapy, including chemotherapy ... -
Orthostatic Hypotension and Cerebral Perfusion in Falls and Related Syncopal Disorders
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, 2025)Falls, syncope and orthostatic dizziness are common reasons for hospital presentations and are highly prevalent among older adults, leading to significant morbidity, loss of independence and increased healthcare utilisation. ... -
The induction of trained immunity through dietary supplementation with b-glucan boosts myeloid anti-tumour immunity in diet induced obesity
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2025)Over the last 10 years, emerging concepts in our understanding of immunological memory have broadened the field to recognise that immunological memory is not a feature that is unique to the mammalian adaptive immune system. ... -
Rational design of particulate vaccine adjuvants for enhanced T cell-mediated immunity
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2025)Resolving the mechanisms underlying the immunostimulatory properties of vaccine adjuvants is critical to provide a basis for rational adjuvanted vaccine design for specific diseases and target groups. Building on this, ... -
Essays in the Economic History of Labour Market Institutions and Industry Location
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Economics, School of Social Science, 2025)This thesis explores the role of institutions, labour relations, and economic geography in shaping long-term economic outcomes. It comprises three essays that empirically analyse how organisational structures respond to ...