Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 201-220 of 7000
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Mycobacterium tuberculosis attenuates Macrophage responses through Pentose Phosphate Pathway activity
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2025)Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is adept at evading host immune defences and establishing chronic infections, particularly within macrophages. Central to its survival is its ability ... -
Investigating the influence of sex differences on modulation of neuroinflammation in the mouse by aerobic exercise
(Trinity College Dublin. School of Medicine. Discipline of Physiology, 2025)Exercise has long been viewed as an 'all-in-one' therapeutic approach by preserving and improving health and reducing the risk of age-associated noncommunicable metabolic, cardiovascular and neurodegenerative diseases ... -
A Randomised Controlled Clinical Trial investigating the effect of osseodensification on implant stability and marginal bone levels.
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2025)Osseointegration is a histologic term defined as the “direct structural and functional connection between living bone and the surface of a load-carrying dental implant”. Achieving successful osseointegration without the ... -
Plasticity of instinct: Interactions of the memory engram with innate behaviour
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2025)The brain has access to two sources of information to guide behaviour; instinct and memory. While research into these two phenomena is advancing rapidly, much less is known about how they interact with one another. This ... -
English in the Connemara Gaeltacht: A Sociophonetic Study of Bilingual and Monolingual Speakers
(Trinity College Dublin. School of Linguistic Speech & Comm Sci. C.L.C.S., 2025)This thesis presents a sociophonetic investigation of Connemara English, comparing the English of 12 native Irish speakers with that of 12 monolingual English speakers. It addresses a research gap in the study of Irish ... -
3D-Printed Air-Cathodes for Microbial Fuel Cells: Advancing Pollutant Removal and Energy Recovery from Wastewater
(Trinity College Dublin. School of Engineering. Disc of Civil Structural & Environmental Eng, 2025)Worldwide, 300 billion m3 of domestic wastewater was produced every year, which contained around 600 billlion kWh of energy. Current wastewater treatment methods, which rely heavily on aeration, are highly energy-intensive, ... -
From the Smart City to Urban Artificial Intelligence: the Case of Guangzhou, China
(Trinity College Dublin. School of Natural Sciences. Discipline of Geography, Department of Geography, 2025)The thesis investigates the integration of artificial intelligence (AI) and smart city initiatives within the urban governance framework of Guangzhou, China, with a focus on their influence on healthcare services and the ... -
Vitamin D and Hair: A review of current methods and validation of a quantitation method to measure 25(OH)D3 from hair
(Trinity College Dublin. School of Medicine. Discipline of Public Health & Primary Care, 2025)Introduction: Hair has emerged as a promising matrix for assessing endogenous steroid hormone levels, yet its potential for the quantitation of vitamin D remains unexploited. Vitamin D status is typically assessed by ... -
Evaluating the Influence of Vocal and Visual Realism on Subjective Experiences of Empathy for Virtual Characters
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2025)With the expanding range of use cases for advancements in animation and voice synthesis, more opportunities arise for interactions with realistic virtual characters. As yet, it is unclear to what extent realism, either in ... -
Essays on the Impact of Military Recruitment Policies on Gender and Ethnic Relations
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Political Science, 2025)This dissertation examines the broader societal ramifications of military recruitment policies on groups that are typically, either explicitly or implicitly, excluded from military institutions: women and ethnic minorities. ... -
Education, Indoctrination and Conflict: The Role of Political Education in Shaping Combatant Behaviour and Sexual Violence in Civil War
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Political Science, 2025)This thesis analyses socialisation patterns within rebel groups in order to explain conflict-related sexual violence (CRSV). Researchers have dedicated extensive studies on the violent behaviour of rebel groups, investigating ... -
Hereditary Haemochromatosis: Hepatic and Cardiac Iron content and cardiac function at baseline and after a treatment course of venesection.
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Background Hereditary haemochromatosis (HH) is the most common inherited genetic disorder in Europe1. Although there are several genetic mutations which can lead to the development of HH, the p.C282Y mutation (tyrosine ... -
Longitudinal brain connectivity derived from the Stop-Signal Task as a predictor of substance use
(Trinity College Dublin. School of Psychology. Discipline of Psychology, 2025)Adolescence is a critical period of brain development and may involve a propensity to engage in risky behaviours, such as substance use. Substance use, including cigarettes and cannabis, is associated with impairments in ... -
Upper mantle structure, intraplate volcanism and the unique anisotropy of the Antarctic Plate from waveform tomography
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2025)Antarctica’s unique geological setting makes it an important location for understanding the Earth’s crust and upper mantle, and its connections to the past and future evolution of the Earth. The Antarctic continent has ... -
The Role of Vascular Ultrasound in GCA-PMR Spectrum Disease
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)Background Timely and accurate identification of ‘GCA-PMR Spectrum Disease’ and its subsets is important so vascular complications can be averted. Traditional diagnostic and monitoring tools such as Temporal Artery ... -
The Covalent Capture of [2]Catenanes Using Self-Templating Allyl Amide-Appended 2,6-bis(triazol-4-yl)pyridines
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)This thesis, entitled "The Covalent Capture of [2]Catenanes Using Self-Templating Allyl Amide-Appended 2,6-bis(triazol-4-yl)pyridines" describes the synthesis of self-templating [2]catenanes using the N-allyl-4-methylene ... -
Taking Play Seriously: Children's Education and Nation-building in Modern China, 1897-1937
(Trinity College Dublin. School of Histories & Humanities. Discipline of History, School of Histories and Humanities, 2025)China’s experience of foreign encroachment in the second half of the nineteenth century was what John Fitzgerald calls a wave of awakening among the intelligentsia. It was in this context that educational reform became ... -
The Impact of Driving Restrictions on People with Epilepsy in Ireland
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Driving restrictions have a significant impact on patients with epilepsy and their families. This is documented in international studies but underreported in an Irish context. The goal of this study was to examine this ... -
Investigating the Mechanisms of Memory Engram Plasticity in Infantile Amnesia
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2025)Infantile amnesia describes the inability to recall memories formed during a critical period of development in infancy and early childhood. While significant advancements have been made in characterizing this phenomenon ...
