Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 221-240 of 7000
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Synthesis and Testing of Lipopeptide and Peptide Probes for Bacterial Lipoprotein Processing Enzymes
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)Bacterial lipoproteins perform essential functions in bacteria and are often crucial for survival, growth and virulence. Bacterial lipoproteins feature a fully conserved N-terminal cysteine bearing a 1,2-diacylglyceryl ... -
Diet and Oral Health of Elite Athletes in Ireland
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, Trinity College Dublin, the University of Dublin, 2025)Introduction: Previous research has indicated a high prevalence of untreated dental disease among elite athletes. Multiple factors may predispose athletes to a high-risk profile including frequent carbohydrate consumption, ... -
Rational catalyst design for photo- and electrochemical hydrogenation reactions
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)Environmental pollution is an urgent threat to human health and the survival of life forms on land and in water. This crisis is fuelled by industrial, agricultural, and biomedical chemical waste, alongside the use of ... -
The Fabrication of Highly Conducting and Thermo-mechanically Robust Metal Thin Film
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)Recent research from high-resolution surface probe microscopy and atomic simulation have identified that grain boundaries in [111] F.C.C. thin copper films can restructure in a region immediately below the surface. DFT ... -
Augmentation of labour with synthetic oxytocin: a mixed methods study
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, School of Nursing and Midwifery, 2025)Background: Augmentation of labour with synthetic oxytocin is one of the most frequently performed childbirth interventions among women with spontaneous onset of labour. Rates of augmentation of labour with synthetic ... -
Reducing the Signaling Overhead of Contemporary and Future Wireless Networks
(Trinity College Dublin. School of Engineering. Discipline of Electronic & Elect. Engineering, 2025)Signaling overhead reduction has always been a challenging task in the design of wireless networks. New applications and services in future networks, such as autonomous vehicles, and deployment of higher frequency bands, ... -
Fluvial Carbon Budgeting Across a Spectrum of Raised Bog Environments.
(Trinity College Dublin. School of Engineering. Disc of Civil Structural & Environmental Eng, 2025)This study set out to determine the feasibility of using in-situ fDOM measurements as a proxy for NPOC, the relationship of which was used to predict the fluvial carbon budget of the three raised bog sites, taking into ... -
Collagen Deposition, Cellular and Molecular characterisation of self-assembled tendon constructs grown in vitro from embryonic chick tenocyte cells
(Trinity College Dublin. School of Natural Sciences. Discipline of Zoology, 2025)Tendons are fibrous connective tissues that connect and transmit forces between muscle and bone. Following injury, they are very difficult to repair surgically, often resulting in tissue that is not comparable to native ... -
Mná Maithe Mumhan `Noble Women of Munster' Bardic poems from the Book of Fermoy in praise of noble women of Munster
(Trinity College Dublin. School of Lang, Lit. & Cultural Studies. Discipline of Irish, 2025) -
Understanding Readiness and Motivation for Digital Mental Health Support
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2025)Psychological therapy is an effective and acceptable form of care for distress, however, there is a vast disparity between the number of people who are suffering and those receiving support. Digital mental health interventions ... -
Semantic Frameworks to Support the EU AI Act's Risk Management and Documentation
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, School of Computer Science and Statistics, 2025)The European Union (EU) Artificial Intelligence Act (AI Act), which entered into force on 1 August 2024, stands as a landmark legal regime for development and use of AI, adopting a risk-based approach to govern the potential ... -
From Theory to Practice: Empowering Teacher Agency and Confidence through Cross-Sectoral Communities of Practice to Implement Universal Design for Learning.
(Trinity College Dublin. School of Education. Discipline of Education, 2025)The literature highlights a critical need for practical, classroom-level guidance on effectively implementing Universal Design for Learning (UDL). Researchers such as Edyburn and Edyburn (2015), Ok et al. (2017), and Rao ... -
Development of novel image-based computational and artificial intelligence (AI) technologies for real time monitoring and event detection during in vitro dissolution testing
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2025)To ensure safe and effective medications, in recent years the ever evolving pharmaceutical industry started to transform and to adopt novel technologies for continuous manufacturing, real time monitoring and quality control. ... -
Thioacid Mediated Methods for Peptide Ligation and Cyclisation
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)In recent years, peptide-based therapeutics have become the focus of intensive research due to their favourable chemical properties. Consequently, the ability to efficiently synthesise a wide range of structurally diverse ... -
Investigation of the role of Mediator tail subunits in antifungal drug resistance and cellular aggregation in Candida species
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2025)Candida albicans is a commensal fungal pathogen that resides on various human mucosal surfaces (e.g. oral cavity) and can cause severe infection in immunocompromised individuals. Azole antifungal resistance in C. albicans ... -
Theoretical developments of modelling techniques and novel visualisations for studying the biodiversity and ecosystem function relationship; and their application for calculating the economic value of biodiversity.
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Statistics, 2025)The biodiversity and ecosystem function (BEF) relationship studies how species diversity within an ecosystem affects the outputs (called ecosystem functions) the system produces. In recent decades, there has been great ... -
Electrical and structural characterisation of Transition Metal Dichalcogenides
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)This thesis explores modification of transition metal dichalcogenides (TMDs) through doping and synthesis techniques to tailor their electronic properties, including sensor technology. The work is divided into three main ... -
Gastrointestinal Bleeding Management and Utility of Clinical Scores in Predicting Disease and Outcome in a Modern European Population
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Acute gastrointestinal bleeding remains a significant clinical challenge, with early risk stratification playing a critical role in guiding management decisions and optimizing patient outcomes. Risk scores, particularly ... -
Investigation of Copper/Graphene Composite Materials for Enhanced Electrical Conductivity Applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)Copper plays a vital and ever-growing role in electrical power and signal transmission in the world today. This is due to its remarkable electrical properties, coupled with its low cost and abundance. In order to satisfy ... -
Radio Imaging Spectroscopy of Eruptions in the Solar Corona
(Trinity College Dublin. School of Physics. Discipline of Physics, 2025)Regularly, the Sun produces a variety of energetic explosive events, such as solar flares (sudden, intense bursts of electromagnetic radiation) and coronal mass ejections (CMEs) (large-scale expulsions of plasma and magnetic ...