Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 321-340 of 7000
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Landscapes of the socio-political : Irish women playwrights from 2000
(Trinity College (Dublin, Ireland). Department of Drama, 2017)This thesis looks at intersections between women, theatre and Irish society since the turn of the millennium. There is a history of internalized misogyny throughout Irish theatre and, in part, the impetus for the study has ... -
Firm-level geographic sales analysis in international equity portfolio diversification'
(Trinity College (Dublin, Ireland). Trinity Business School, 2017)Recent research has shown a decrease in the benefits of international diversification for developed market equities and finds that diversifying an equity portfolio across countries offers a lower potential for risk-reduction ... -
Engineering of itraconazole nano- and microparticles with improved pharmaceutical performance
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2016)Itraconazole (ITR) is an antifungal drug with limited bioavailability due to its poor aqueous solubility. In this work, ITR was used to investigate unexplored and/or previously reported as infeasible formulation approaches ... -
Development of glycosylated molecular scaffolds as potential anti-cancer therapeutics
(Trinity College (Dublin, Ireland). School of Chemistry, 2016)The requirement for cell-type specific targeting of anti-cancer therapeutics is crucial to improve treatment and the pallitive care of patients. In this regard, the field of glycotherapeutics has witnessed a surge in ... -
Dignity and duty : a dignity based account of human rights and their associated duties
(Trinity College (Dublin, Ireland). Department of Political Science, 2017)This thesis is primarily motivated by a perceived gap in the literature on human rights in how that literature deals with the duties associated with human rights. I argue that we do not have a clear and coherent understanding ... -
Towards fit for purpose final assessment of clinical skills in medical graduates
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Surgery, 2017)Background: The assessment of broader competencies of skills and attributes beyond knowledge are expected graduate outcomes in a medical degree. Assessment must provide explicit evidence of student learning. The quality ... -
Warding off evil : an analysis of apotropaic tradition in the Dead Sea Scrolls and Synoptic Gospels
(Trinity College (Dublin, Ireland). Department of Religions and Theology, 2016)This thesis is comprised of five chapters which address human responses to personified evil in the Dead Sea Scrolls and the synoptic gospels. One response, exorcism, is prevalent in each of the synoptics and has been given ... -
Exploring the role of lipoxygenases in oesophageal cancer and the anti-angiogenic potential of novel lipoxgenase inhibitors
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Surgery, 2016)Over the past decade there has been a dramatic increase in the incidence of oesophageal cancer in Ireland, which has the third highest incidence rate in Europe. This is mainly due to rising numbers of the oesophageal ... -
Post-genomic investigation of coeliac susceptibility genes
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2017)Coeliac Disease (C) is a debilitating condition characterised by chronic inflammation of the small intestine. This autoimmune disorder is triggered in genetically predispsed individuals following ingestion of dietary gluten, ... -
Constitutional equality law and the right to education : tackling poverty and class inequality through public interest law
(Trinity College (Dublin, Ireland). School of Law, 2017)This thesis is a study of the constitutional implications of inequality on the basis of poverty, social class and socio-economic status in the education system in Ireland. The core research question is whether the Constitution ... -
Essays on synergies from the geographic clustering of literary artists
(Trinity College (Dublin, Ireland). Department of Economics, 2017)This thesis consists of five chapters on synergies from the geographic clustering of literary artists. Chapter 1 provides an introduction to the thesis. Chapter 2 utilises a unique, purpose built panel dataset on prominent ... -
Healthcare environmental reservoirs of infection : investigating water systems and the use of electrochemically activated solution Ecasol as a versatile disinfectant
(Trinity College (Dublin, Ireland). School of Dental Science, 2016)A reservoir of infection is any site in which viable infectious agents can live and grow. Healthcare associated infections (HCAIs) are caused by the acquisition of infectious agents by patients during the course of their ... -
Video Compression Artifact Suppression Using Perceptual Criteria
(Trinity College Dublin. School of Engineering. Discipline of Electronic & Elect. Engineering, 2025)This thesis explores the application of perceptually motivated optimization techniques in training neural networks for suppressing video compression artifacts. These techniques aim to align optimization criteria with the ... -
Analysis of the mechanism of protein A release and its contribution to immune evasion by Staphylococcus aureus
(Trinity College (Dublin, Ireland). Department of Microbiology, 2016)The immunoglobulin binding protein A (SpA) of Staphylococcus aureus was one of the first cell wall-associated proteins of Gram-positive bacteria to be identified and characterised. It is synthesized as a precursor with a ... -
Essays on the transmission channels of macroeconomic policy
(Trinity College (Dublin, Ireland). Department of Economics, 2016)This thesis consists of three empirical essays, examining the channels through which macroeconomic policy variables can affect the domestic economy. The essays analyse monetary and fiscal policy, identifying dimensions ... -
The impact of kynurenine pathway activation in glia on neuronal integrity
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2017)The kynurenine pathway, which is activated in times of stress and infection has been implicated in the pathophysiology of neurodegenerative and psychiatric disorders. Alterations in neuronal integrity, including neuronal ... -
The liquid phase exfoliation of transition metal oxides for high energy metal oxides for high energy Li-ion batteries
(Trinity College (Dublin, Ireland). School of Chemistry, 2017)Compared to other electrochemical energy sources, lithium ion (Li-ion) batteries represent the choice energy storage device for small hand held electronics such as power tools or cellphones. This is due mainly to the balance ... -
Idir shúgradh agus dáiríre : grá riabhach Bhiddy Jenkinson
(Trinity College (Dublin, Ireland). Department of Irish and Celtic Studies, 2017)File, drámadóir, gearrscéalaí agus úrscéalaí í 'Biddy Jenkinson' atá ag foilsiú faoin ainm pinn sin le 35 bliain anuas. Ainneoin go n-áirítear í ar na scríbhneoirí Gaeilge is tábhachtaí agus is bisiúla sa lá atá inniu ann, ... -
Inequality, crime and property offences : a critical analysis of theft in Ireland
(Trinity College (Dublin, Ireland). School of Law, 2016)Inequality, crime and property offences interact and intersect across multiple different spheres. Disentangling the relationship between them requires analysis of economics, sociology, culture, history, law and philosophy, ... -
The role of natural killer cells in the immune response to hepatitis C virus
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2016)Hepatitis C virus (HCV) infection remains a major clinical problem, particularly in the developing world where high cost makes treatment inaccessible to many. Those coinfected with HIV also face poorer prognosis and increased ...
