Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 441-460 of 7000
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Importance of energy metabolism, angiogenesis and DNA repair in regulating neoadjuvant radiosensitivity in oesophageal and rectal adenocarcinoma
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Surgery, 2016)Oesophageal and rectal adenocarcinoma are treated with neoadjuvant chemoradiotherapy in order to reduce tumour size prior to surgery, however only 10- 30% of patients have a complete pathological response and there are no ... -
An investigation of the intellectual skill implicit in the aims and assessment of some subjects in the Leaving Certificate in Ireland 2005 - 2010
(Trinity College (Dublin, Ireland). School of Education, 2016)The study investigated the intellectual skills implied by the syllabi and required by the examination papers in 23 Leaving Certificate subjects from 2005 to 2010. The study included the consideration as to what intellectual ... -
Delineating the impact of executive dysfunction on social cognition for patients and caregivers in Amyotrophic Lateral Sclerosis
(Trinity College (Dublin, Ireland). Institute of Neuroscience, 2016)Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressive neurodegenerative disease that implicates both motor and cognitive function, and is the most prevalent Motor Neuron Disease (MND). ALS is a clinically heterogeneous ... -
Synthetic approaches towards thioester-mediated biocojugation and lanthanide-based glycoconjugate probes
(Trinity College (Dublin, Ireland). School of Chemistry, 2017)This thesis, entitled "Synthetic Approaches Towards Thioester-Mediated Bioconjugation and Lanthanide-Based Glycoconjugate Probes" is divided into six chapters. Chapter 1, the introduction, firstly introduces the concept ... -
Bone health in older adults with an intellectual disability
(Trinity College (Dublin, Ireland). School of Nursing & Midwifery, 2016)Intellectual disability (ID) is characterised by significant limitations of both adaptive behaviour and intellectual functioning. It is a prescribed term to describe a common understanding of what is being discussed or ... -
Speculators in conflict : the Adventurers and the Wars of the Three Kingdoms, 1642 - 1660
(Trinity College (Dublin, Ireland). Department of History, 2016)This study reveals how the actions of an extraordinary group of skilled and innovative individuals, less than twenty in number, developed and maintained a stable system of state finance in highly challenging times. They ... -
Experimental and numerical investigation of a Photovoltaic/Thermal/Phase Change Material System
(Trinity College (Dublin, Ireland). Department of Civil, Structural and Environmental Engineering, 2016)Hybrid Photovoltaic/Thermal (PV/T) systems generate both electricity and heat simultaneously. Typically 15 - 18 % of solar radiation incident on a PV module is converted to electricity and 82 - 85 % is converted to heat. ... -
Investigations of mechanisms of drug-resistance and associated biomarkers in HER2-overexpressing breast cancer
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2016)Breast cancer is the most commonly diagnosed cancer amongst women in Ireland. HER2-overexpressing breast cancer accounts for 25-30% of all breast cancer cases and was the focus of this project. While treatment options for ... -
Twilight zones : subjectivity, gender, and feminism in three 21st century popular vampire romance narratives
(Trinity College (Dublin, Ireland). School of English, 2016)This thesis examines three century American vampire romance narratives: the Twilight novels (2005-2008) by Stephenie Meyer and their film adaptations (2008-2012), the HBO television adaptation of Charlaine Harris' Southern ... -
The role of ceramics in Protopalatial East Crete, as observed at Priniatikos Pyrgos : a study in socio-economic interaction through design and exchange
(Trinity College (Dublin, Ireland). Department of Classics, 2017)This thesis is a critical assessment of the regional role of Priniatikos Pyrgos (PP) in Mirabello Bay and Central-East Crete during the Protopalatial period of the Minoan Bronze Age. The chronological range of this study ... -
The depiction of Muslims in contemporary Latin narratives of the First Crusade
(Trinity College (Dublin, Ireland). Department of History, 2017)Although they undoubtedly drew on knowledge that existed in Western Europe, the authors of histories the First Crusade lacked an authoritative source on Islam. As such, in trying to give more complete depictions of Muslims, ... -
The Herrero conditions on norm limits of hypercyclic operators
(Trinity College (Dublin, Ireland). School of Mathematics, 2017)Abstract. For a separable infinite dimensional Banach space X it is known that X supports many bounded linear operators T which are hypercyclic, that is such that there is a vector x E X with dense orbit {x, Tx, T2x,...}. ... -
Multifaceted sensors based on conductive nanocomposites
(Trinity College (Dublin, Ireland). School of Physics, 2016)With such superlative properties, nanomaterials have been of great interest in recent times and have undergone intense research in many disciplines for a wide variety of applications. Of particular interest, is the use of ... -
Modelling and monitoring geomagnetically induced currents in Ireland
(Trinity College (Dublin, Ireland). School of Physics, 2017)This thesis is the first detailed study of the effects of geomagnetic storms and geomagnetically induced currents (GICs) on the Irish power network. In order to better monitor geomagnetic storms in Ireland, a network of ... -
Essays in macroeconomics and finance
(Trinity College (Dublin, Ireland). Department of Economics, 2017)This dissertation consists of three essays, which deal with issues relating to the financial sector. Although the three chapters are independent, a common underlying theme is financial crises. The first essay studies the ... -
The incorporation of expert evidence in Ireland
(Trinity College (Dublin, Ireland). School of Law, 2017)This thesis concerns the incorporation of expert evidence into Irish criminal and civil proceedings. The methodology employed in this thesis is doctrinal legal analysis. It is the product of extensive and detailed analysis ... -
Investigating the role of the transcription factor Rorα in macrophages in the context of development, inflammation and circadian rhythms
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2016)Macrophage subsets in tissue sites such as the peritoneal cavity are extremely heterogeneous in their phenotype and functions. These peritoneal macrophage subsets can be of dual origin: monocyte-derived or tissue-resident ... -
The Problem of Control in Data Protection Law
(Trinity College Dublin. School of Law. Discipline of Law, 2024)Introduced in 2016, the General Data Protection Regulation ('GDPR') marked a significant shift in the balance between individual privacy on one side and the increasingly entwined forces of multinational tech commerce and ... -
Children's ability to identify and describe dysphonia: A multimethod study
(Trinity College Dublin. School of Linguistic Speech & Comm Sci. Discipline of Clin Speech & Language Studies, 2024)Background: While some studies have demonstrated that children can express opinions about their voice, and that they are conscious of and affected by their voice disorders, knowledge about age-related understanding of ... -
Understanding the Social and Technical Challenges of Fairness in Digital Health
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2024)Fairness is broadly defined as the act of treating similar people similarly and in line with social norms. It is not a new topic of research. Fairness, as it relates to ethics and justice, has been a topic of discussion ...
