Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 561-580 of 7000
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Balancing Innovation with Environmental Sustainability: Vapour Phase Patterning System for Controlling Block Co-Polymer and Polymer Brush Morphology
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The growth of the semiconductor industry and device miniaturisation has highlighted a need for novel and sustainable approaches to nanofabrication. Resource scarcity, increasing energy costs and environmental instability ... -
An Investigation into Micro-level Corporate Social Responsibility: An Internal Stakeholder Perspective
(Trinity College Dublin. School of Business. Discipline of Business & Administrative Studies, 2024)Scholars in the field of corporate social responsibility (CSR) have primarily focused on how institutional and firm-level factors influence CSR performance, while individual-level factors (or micro-level), particularly the ... -
Polish Complementary Schools in Ireland: Language, Heritage, Capital
(Trinity College Dublin. School of Linguistic Speech & Comm Sci. C.L.C.S., TCD School of Linguistic, Speech and Communication Sciences, 2024)In recent decades, multiple cultures and languages have significantly enriched Irish society and classrooms due to increased inward migration. Many migrant families aim to maintain and transmit their linguistic and cultural ... -
Mutual Support Between Patients and Family Caregivers in Palliative Care
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2024)Background: Palliative care is an interdisciplinary care approach to improve quality of life and alleviate symptom distress for people living with life-limiting conditions and their families. A systematic review conducted ... -
Reconceptualising Eco-tourism: Aligning Tourism and Conservation Goals using Biodiversity Perception, Governance, and Management
(Trinity College Dublin. School of Natural Sciences. Discipline of Zoology, Trinity College Dublin, School of Natural Sciences, 2024)This thesis represents an in-depth exploration of the intricate relationship between tourism and conservation, delving into the critical need for robust governance to ensure effective environmental management within the ... -
High Resolution Lithography Techniques for Applications in Plasmonic Nanomaterials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Metallic nanoparticles are of great scientific interest owing to their ability to support collective oscillations of electrons across their surface, known as localised surface plasmon resonances (LSPRs), when illuminated ... -
Assessment of milk extracellular vesicle (EV) in vitro bioactivity
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, School of pharmacy and pharmaceutical science, 2024)Extracellular Vesicles (EVs) are small particles involved in cell-to-cell communication. They have been identified in numerous biological fluids, including milk. Milk EVs serve to communicate between mother and infant, ... -
Cell landscape of immunosuppressive reprogramming during fatal sepsis and severe-COVID-19 through scRNA-SEQ
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)It is evident that some patients with sepsis and septic shock are admitted to hospitals late in their illness, contributing to poor outcomes and high mortality rates across all age groups worldwide. Current diagnostic and ... -
Divine Omnipotence: Aquinas and Swinburne
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Philosophy, 2024)Abstract The goal of this thesis is to establish whether Thomas Aquinas's conception of God's omnipotence can survive critical interaction with the views of Richard Swinburne. It first defines in detail what Aquinas thinks ... -
European Architectural Draughtsmen in Early Eighteenth-Century Britain and Ireland: Training, Methods, Office Practice
(Trinity College Dublin. School of Histories & Humanities. Discipline of History Of Art, 2024)The thesis examines the careers of Richard Castle and Johann Gottlieb Borlach, two German draughtsmen who joined the architectural practices of Sir Edward Lovett Pearce and James Gibbs in the first half of the eighteenth ... -
The Irish Record Commission (1810-1830) Medievalism and the Emergence of Archivism in Ireland
(Trinity College Dublin. School of Histories & Humanities. Discipline of History, 2024)The aim of this study is to investigate the role and remit of the Irish Record Commission 1810-1830, a commission set up to look into the state of record repositories in Ireland and organise and make accessible the records ... -
The role of tissue resident memory T cells in the respiratory mucosal immune response in humans
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, School of Biochemistry and Immunology, 2024)Tissue resident memory T (TRM) cells represent a population of effector memory T cells that persist in peripheral tissues and act as sentinels of the adaptive immune response, facilitating rapid and specific immune responses ... -
NOX2-mediated regulation of NLRP3 inflammasome activation in traumatic brain injury
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2024)Traumatic brain injury (TBI) is described as damage to the brain due to a mechanical impact to the head and is the leading cause of death and disability in developed countries. Following the primary mechanical injury, ... -
An Evaluation of In-Hospital Stroke in Irish Acute Hospitals
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)Introduction Between 1 and 17% of strokes occur in-hospital in patients hospitalised for another reason. In-hospital strokes are associated with worse outcomes and poor performance on quality-of-care measures of acute ... -
Pharmaceutical Solid Forms and Formulations for Enhanced Solubility and Dissolution: Cocrystals, Salts, and Crystalline Solid Dispersions
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2024)This thesis focuses on the development, manufacture, and characterisation of cocrystals and salts and their formulations, to enhance the solubility and dissolution of poorly soluble drugs. Three poorly soluble active ... -
Quantitative proteomics of natural dendritic cell subsets
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2024)Dendritic cells (DCs) are a critical bridge between innate and adaptive immunity. They are a heterogeneous population composed of various subsets that modulate different aspects of the immune response. It is now clear that ... -
Biological Ageing: A study of telomere length and mitochondrial DNA copy number in anorexia nervosa
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)INTRODUCTION Patients with anorexia nervosa (AN) experience significant psychological and physical stress, which are risk factors for accelerated biological ageing. Telomeres are protective caps at the ends of chromosomes ... -
Exploiting Connected Autonomous Vehicles to Improve Mixed Traffic Safety and Efficiency in Realistic Scenarios
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2024)Human-driven vehicles (HDVs) produce stop-and-go waves i.e., high speed variations, due to humans large-reaction times and perception errors. This leads to decrease in both traffic safety and efficiency. In contrast, ... -
Metabolic Syndrome and Accelerated Biological Ageing
Introduction: Metabolic syndrome consists of the cluster of obesity, insulin resistance, hypertension, and atherogenic dyslipidaemia. This syndrome is a risk factor for all-cause mortality but has not been well characterised ... -
A Participatory Action Research Study on Separated Migrant Youth Experiences in Northern France
(Trinity College Dublin. School of Social Work & Social Policy. Discipline of Social Studies, 2024)This thesis examines separated young people’s transitions to adulthood in Northern France. The emergent research literature on separated children and youth has identified the transition to adulthood as a particularly ...
