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dc.contributor.advisorLawler, Mark
dc.contributor.authorForde, James Christopher
dc.date.accessioned2017-05-15T14:16:48Z
dc.date.available2017-05-15T14:16:48Z
dc.date.issued2010
dc.identifier.citationJames Christopher Forde, 'The role of HIF-lalpha and hypoxia in the preferential response of prostate tumours to microtubule-targeting agents', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2010, pp 132
dc.identifier.otherTX-1-865
dc.description.abstractTumour hypoxia is emerging as a common feature of prostate tumours associated with poor prognosis mainly due to their resistance to chemo- radiotherapy regimes. The efficacy of microtubule-targeting agents (MTAs) has recently been shown to be modulated by Hypoxia-Inducible-Factor-1 alpha (HIF-1α). HIF- 1α over expression has been reported to occur in almost 70% of all human tumours including prostate cancer.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb14882831
dc.subjectClinical Medicine, M.D.
dc.subjectM.D. Trinity College Dublin
dc.titleThe role of HIF-lalpha and hypoxia in the preferential response of prostate tumours to microtubule-targeting agents
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelBachelor of Science
dc.type.qualificationnameDoctor of Medicine (M.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 132
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie
dc.identifier.urihttp://hdl.handle.net/2262/80024


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