Synthesis and investigation of transaminase mimics

Abstract

Chiral amines have been the subject of much attention in view of their wide scope of applications ranging from catalysts in asymmetric synthesis to intermediates for pharmaceuticals and agrochemicals. Consequently, a great deal of methodology for the preparation of such valuable compounds has been developed. Nature accomplishes this task with efficiency in the case of the a-amino acids via the transamination process which consists of the transfer of an amino group from a starting amine to a carbonyl compound.